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Ann Gastroenterol. 2019 May-Jun;32(3):298-302. doi: 10.20524/aog.2019.0367. Epub 2019 Mar 12.

Impact of body mass index on the incidence and severity of post-endoscopic retrograde cholangiopancreatography pancreatitis.

Annals of gastroenterology

Mohamed M Abdelfatah, Nicholas J Koutlas, Eric Gochanour, Ahmed Hamed, Mariam Ibrahim, Mohamed Barakat, Prashant R Mudireddy

Affiliations

  1. Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, East Carolina University, Greenville, NC (Mohamed M. Abdelfatah, Nicholas J. Koutlas, Eric Gochanour, Ahmed Hamed, Mariam Ibrahim, Prashant R. Mudireddy).
  2. Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Emory University, Atlanta, GA (Mohamed M. Abdelfatah), USA.
  3. Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, The Brooklyn Hospital Center, Bbrooklyn, NY (Mohamed Barakat), USA.

PMID: 31040628 PMCID: PMC6479648 DOI: 10.20524/aog.2019.0367

Abstract

BACKGROUND: Pancreatitis is a potential major complication after endoscopic retrograde cholangiopancreatography (post-ERCP pancreatitis; PEP). Obesity has been associated with increased severity of acute pancreatitis. However, the correlation between obesity and PEP is controversial. Therefore, our study aimed to clarify the relationship between body mass index (BMI) and the incidence and severity of PEP.

METHODS: A retrospective cohort study was conducted to elucidate the relationship between BMI and PEP in all patients who underwent ERCP in a tertiary referral center between January 2009 and October 2016. Patient characteristics and procedure details were collected. PEP was defined by consensus criteria. Multivariate logistic regression was used to determine the association between BMI and PEP.

RESULTS: The analysis included 2236 patients whose BMI was recorded and had adequate follow up (921 with BMI≥30 kg/m

CONCLUSION: In the largest study to date, neither obesity nor low body weight increased the incidence or severity of PEP.

Keywords: Obesity; body mass index; post-ERCP pancreatitis; underweight

Conflict of interest statement

Conflict of Interest: None

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