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J Family Med Prim Care. 2019 Mar;8(3):1257-1259. doi: 10.4103/jfmpc.jfmpc_25_19.

Acute parvovirus B19 infection presenting as rheumatoid arthritis mimic.

Journal of family medicine and primary care

Vijay Alexander, Sohini Das, Austin Saju Mangan, Ramya Iyadurai

Affiliations

  1. Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.

PMID: 31041286 PMCID: PMC6482719 DOI: 10.4103/jfmpc.jfmpc_25_19

Abstract

Acute parvovirus B19 infection can cause acute symmetric polyarthritis indistinguishable from polyarticular rheumatoid arthritis. Most cases of acute arthritis due to parvovirus B19 are self-limiting and resolve with symptomatic treatment. We present a 65-year-old lady from Southern India who presented with history of fever and joint pain for 10 days. Clinical examination revealed symmetric inflammatory arthritis involving the appendicular skeleton with predominant involvement of bilateral metacarpophalageal joints. Laboratory investigations revealed elevated inflammatory markers with negative serology for rheumatoid arthritis. Parvovirus B19 IgM antibody tested positive. She was initiated on nonsteroidal anti-inflammatory drugs with which her symptoms resolved completely.

Keywords: Arthritis; parvovirus B19; rheumatoid arthritis

Conflict of interest statement

There are no conflicts of interest.

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