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Case Rep Womens Health. 2019 Apr 03;22:e00111. doi: 10.1016/j.crwh.2019.e00111. eCollection 2019 Apr.

Hyperprolactinemia associated with macroprolactinoma in a 17-year-old: A case report.

Case reports in women's health

Adam Czyzyk, Rafal Kurzawa

Affiliations

  1. VitroLive, The Fertility Partnership, 2A Kasprzaka St., 71-074 Szczecin, Poland.
  2. Department of Gynecology and Reproductive Health, Pomeranian Medical University, 48 ?o?nierska St., 71-210 Szczecin, Poland.

PMID: 31016137 PMCID: PMC6465757 DOI: 10.1016/j.crwh.2019.e00111

Abstract

Hyperprolactinemia is a relatively common endocrine disorder. In women of reproductive age it may present as the amenorrhea-galactorrhea syndrome, but in milder forms also as menstrual abnormalities or infertility. Here we describe a 17-year-old girl previously treated with a combined oral contraceptive due to secondary amenorrhea. Hormonal tests showed hypogonadotropic hypogonadism with severe hyperprolactinemia (PRL concentration 1639 ng/ml). Further tests confirmed the presence of a pituitary macroadenoma. Cabergoline treatment was effective in the restoration of a spontaneous menstrual cycle and PRL normalization. In conclusion, clinicians should be aware of the diagnostic and therapeutic problems in the management of hyperprolactinemia.

Keywords: Hyperprolactinemia; PRL; Prolactinoma; Secondary amenorrhea

References

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