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Arch Med Sci. 2019 May;15(3):666-672. doi: 10.5114/aoms.2019.82670. Epub 2019 Jan 30.

Perinatal outcome of .

Archives of medical science : AMS

Iwona Szymusik, Katarzyna Kosinska-Kaczynska, Maria Krowicka, Milena Sep, Piotr Marianowski, Miroslaw Wielgos

Affiliations

  1. 1 Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland.
  2. Students' Research Group at the 1 Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland.

PMID: 31110532 PMCID: PMC6524192 DOI: 10.5114/aoms.2019.82670

Abstract

MATERIAL AND METHODS: An observational retrospective case control study was carried out. The study population consisted of 644 women in singleton pregnancies (336 IVF/intracytoplasmic sperm injection (ICSI); 308 controls) who delivered > 22 weeks of gestation at the 1

RESULTS: The two study groups were initially matched for age and parity and were also similar with regard to BMI and gestational weight gain. The IVF treatment increased the odds of having vaginal bleeding in the first trimester (OR = 1.68; 95% CI: 1.0-2.86), placenta previa (OR = 5.15; 95% CI: 1.1-33.9), preterm delivery (OR = 2.06; 95% CI: 1.16-3.68), newborn's low birth weight (OR = 2.27; 95% CI: 1.19-4.36) and elective cesarean section (OR = 2.39; 95% CI: 1.7-3.4).

CONCLUSIONS: The IVF singleton pregnancies have an increased risk of adverse perinatal outcome, among which prematurity remains the greatest problem. Therefore, they should be managed as high risk not only due to psychological reasons.

Keywords: in vitro fertilization obstetric outcome; in vitro fertilization pregnancy; pregnancy complications; preterm delivery

Conflict of interest statement

The authors declare no conflict of interest.

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