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Mahle A, Dashaputre N, DeShong P, et al. Catanionic Surfactant Vesicles as a New Platform for probing Glycan-Protein Interactions. Adv Funct Mater. 2018;28(13)doi: 10.1002/adfm.201706215.
Mahle, A., Dashaputre, N., DeShong, P., & Stein, D. C. (2018). Catanionic Surfactant Vesicles as a New Platform for probing Glycan-Protein Interactions. Advanced functional materials, 28(13), . https://doi.org/10.1002/adfm.201706215
Mahle, Amanda, et al. "Catanionic Surfactant Vesicles as a New Platform for probing Glycan-Protein Interactions." Advanced functional materials vol. 28,13 (2018). doi: https://doi.org/10.1002/adfm.201706215
Mahle A, Dashaputre N, DeShong P, Stein DC. Catanionic Surfactant Vesicles as a New Platform for probing Glycan-Protein Interactions. Adv Funct Mater. 2018 Mar 28;28(13). doi: 10.1002/adfm.201706215. Epub 2018 Jan 19. PMID: 31118878; PMCID: PMC6527319.
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Adv Funct Mater. 2018 Mar 28;28(13). doi: 10.1002/adfm.201706215. Epub 2018 Jan 19.

Catanionic Surfactant Vesicles as a New Platform for probing Glycan-Protein Interactions.

Advanced functional materials

Amanda Mahle, Neeraja Dashaputre, Philip DeShong, Daniel C Stein

Affiliations

  1. Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742.
  2. Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742.

PMID: 31118878 PMCID: PMC6527319 DOI: 10.1002/adfm.201706215

Abstract

Glycomics lags substantially behind proteomics and genomics in its ability to decipher and synthesize complex glycans. The slow progress in deciphering glycan interactions at a molecular level is in large part due to the absence of a functional system to express, on a large scale, carbohydrates of known structure, in the context of a biologically relevant assay system. Here we describe the characterization of a glycan-functionalized catanionic surfactant vesicles (CVs) as a platform for glycan synthesis, and to demonstrate that the resulting glycan-functionalized CVs can serve as a scaffold for the interrogation of protein-glycan interactions. We demonstrate that

Keywords: Microcontact Printing; Nanoimprinting; Nanoparticles; Self-Assembly; Surface Modification

References

  1. J Exp Med. 2000 Mar 20;191(6):949-60 - PubMed
  2. J Bacteriol. 2002 Dec;184(23):6410-6 - PubMed
  3. Appl Microbiol. 1965 Mar;13:171-4 - PubMed
  4. Nat Immunol. 2008 Jun;9(6):593-601 - PubMed
  5. Hybridoma (Larchmt). 2008 Apr;27(2):71-9 - PubMed
  6. J Am Chem Soc. 2009 Apr 22;131(15):5471-7 - PubMed
  7. J Proteome Res. 2009 Sep;8(9):4301-10 - PubMed
  8. Colloids Surf B Biointerfaces. 2010 Feb 1;75(2):441-7 - PubMed
  9. Lab Chip. 2010 Feb 21;10(4):477-83 - PubMed
  10. Annu Rev Biochem. 2011;80:797-823 - PubMed
  11. Talanta. 2012 Mar 15;91:134-9 - PubMed
  12. Nat Methods. 2012 Jul;9(7):671-5 - PubMed
  13. J Proteome Res. 2012 Dec 7;11(12):5781-93 - PubMed
  14. Clin Vaccine Immunol. 2014 Feb;21(2):212-26 - PubMed
  15. Chem Biol. 2014 Jan 16;21(1):1-15 - PubMed
  16. Science. 1989 Sep 22;245(4924):1371-4 - PubMed
  17. Arch Biochem Biophys. 1967 Jul;121(1):88-95 - PubMed
  18. J Bacteriol. 1983 Apr;154(1):269-77 - PubMed
  19. J Biol Chem. 1975 Nov 10;250(21):8518-23 - PubMed

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