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Stem Cells Int. 2019 May 19;2019:2945435. doi: 10.1155/2019/2945435. eCollection 2019.

Pharmacological Transdifferentiation of Human Nasal Olfactory Stem Cells into Dopaminergic Neurons.

Stem cells international

Audrey Chabrat, Emmanuelle Lacassagne, Rodolphe Billiras, Sophie Landron, Amélie Pontisso-Mahout, Hélène Darville, Alain Dupront, Francis Coge, Esther Schenker, David Piwnica, Emmanuel Nivet, François Féron, Clotilde Mannoury la Cour

Affiliations

  1. Institut de Recherches Servier, Croissy sur Seine 78290, France.
  2. Aix Marseille University, CNRS, Institut Neurophysiopathologie, Marseille, France.
  3. CIC Biothérapies: Inserm CBT-1409, Marseille, France.

PMID: 31236114 PMCID: PMC6545791 DOI: 10.1155/2019/2945435

Abstract

The discovery of novel drugs for neurodegenerative diseases has been a real challenge over the last decades. The development of patient- and/or disease-specific

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