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MacKerricher W, Klein RR, Winston DC. Association of Antemortem Central Nervous System Symptoms and Location of Aortic Dissections; A Retrospective Study from 2001-2014. Acad Forensic Pathol. 2016;6(3):517-523doi: 10.23907/2016.051.
MacKerricher, W., Klein, R. R., & Winston, D. C. (2016). Association of Antemortem Central Nervous System Symptoms and Location of Aortic Dissections; A Retrospective Study from 2001-2014. Academic forensic pathology, 6(3), 517-523. https://doi.org/10.23907/2016.051
MacKerricher, Wendy, et al. "Association of Antemortem Central Nervous System Symptoms and Location of Aortic Dissections; A Retrospective Study from 2001-2014." Academic forensic pathology vol. 6,3 (2016): 517-523. doi: https://doi.org/10.23907/2016.051
MacKerricher W, Klein RR, Winston DC. Association of Antemortem Central Nervous System Symptoms and Location of Aortic Dissections; A Retrospective Study from 2001-2014. Acad Forensic Pathol. 2016 Sep;6(3):517-523. doi: 10.23907/2016.051. Epub 2016 Sep 01. PMID: 31239925; PMCID: PMC6474547.
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Acad Forensic Pathol. 2016 Sep;6(3):517-523. doi: 10.23907/2016.051. Epub 2016 Sep 01.

Association of Antemortem Central Nervous System Symptoms and Location of Aortic Dissections; A Retrospective Study from 2001-2014.

Academic forensic pathology

Wendy MacKerricher, Robert R Klein, David C Winston

Affiliations

  1. University of Arizona - Pathology.
  2. Pima County Office of the Medical Examiner.

PMID: 31239925 PMCID: PMC6474547 DOI: 10.23907/2016.051

Abstract

Aortic dissections (AD) are a frequent cause of sudden death and are typically associated with chest, back, and/or abdominal pain. Several cases of AD with neurologic presenting symptoms, such as paresthesia, headache, and seizures were noted at the Pima County Office of the Medical Examiner (PCOME) in Tucson, Arizona. Our aim was to compare the location of AD with central nervous system (CNS) versus classic symptoms. Retrospective data were collected from the archives at the PCOME from 2001-2014. There were 61 natural death cases involving the aorta with known antemortem symptoms; 43 cases of AD with classic (non-CNS) symptoms and 18 cases with CNS symptoms. The cases were classified based on Debakey and Stanford classification systems. Patients with CNS symptoms had a greater proportion of Debakey type II dissections (44%) than without CNS symptoms (16%). This association was statistically significant (

Keywords: Aortic dissection; Autopsy; Central nervous system symptoms; Forensic pathology

Conflict of interest statement

DISCLOSURES & DECLARATION OF CONFLICTS OF INTEREST The authors, reviewers, editors, and publication staff do not report any relevant conflicts of interest

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