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Boyanov MA. WHOLE BODY AND REGIONAL BONE MINERAL CONTENT AND DENSITY IN WOMEN AGED 20-75 YEARS. Acta Endocrinol (Buchar). 2016;12(2):191-196doi: 10.4183/aeb.2016.191.
Boyanov, M. A. (2016). WHOLE BODY AND REGIONAL BONE MINERAL CONTENT AND DENSITY IN WOMEN AGED 20-75 YEARS. Acta endocrinologica (Bucharest, Romania : 2005), 12(2), 191-196. https://doi.org/10.4183/aeb.2016.191
Boyanov, M A. "WHOLE BODY AND REGIONAL BONE MINERAL CONTENT AND DENSITY IN WOMEN AGED 20-75 YEARS." Acta endocrinologica (Bucharest, Romania : 2005) vol. 12,2 (2016): 191-196. doi: https://doi.org/10.4183/aeb.2016.191
Boyanov MA. WHOLE BODY AND REGIONAL BONE MINERAL CONTENT AND DENSITY IN WOMEN AGED 20-75 YEARS. Acta Endocrinol (Buchar). 2016 Apr-Jun;12(2):191-196. doi: 10.4183/aeb.2016.191. PMID: 31149086; PMCID: PMC6535291.
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Acta Endocrinol (Buchar). 2016 Apr-Jun;12(2):191-196. doi: 10.4183/aeb.2016.191.

WHOLE BODY AND REGIONAL BONE MINERAL CONTENT AND DENSITY IN WOMEN AGED 20-75 YEARS.

Acta endocrinologica (Bucharest, Romania : 2005)

M A Boyanov

Affiliations

  1. University Hospital Alexandrovska, Clinic of Endocrinology and Metabolic Diseases, Medical University of Sofia, Faculty of Medicine, Department of Internal Medicine, Sofia, Bulgaria.

PMID: 31149086 PMCID: PMC6535291 DOI: 10.4183/aeb.2016.191

Abstract

BACKGROUND: Dual-energy X-ray absorptiometry (DXA) allows measurement of whole body (WB) and regional bone mineral content (BMC) and density (BMD).

OBJECTIVE: To measure WB and regional bone area, BMC and BMD (arms, legs, ribs and pelvis) in women of different ages.

SUBJECTS AND METHODS: 140 women participated (age range 20-75 yrs). Three subgroups were built: 20-44 yr (30 premenopausal women), 45-59 (80 women), and 60-75 (30 women). WB DXA was performed on a Hologic QDR 4500 A bone densitometer (Hologic Inc., Bedford MA). WB BMD T-scores were calculated by using the manufacturer-provided and the NHANES 1999-2004 reference databases, while the WB BMC Z-scores - based on the latter. Statistical analysis was performed on an IBM SPSS Statistics 19.0 for Windows platform (Chicago, IL).

RESULTS: WB BMC and BMD Z-scores were consistently lower than the reference databases showing a difference of about 0.4 - 0.5 SD. The arms, legs and ribs lost more BMC after the age of 50-55, while the pelvis - much earlier. The total decreases in BMC were highest in the pelvis (26.36 %), followed by the arms (16.81 %) and whole body (15.91 %), while the bone area decreased mostly in the pelvis (13.23 %).

CONCLUSION: The age-related declines in regional BMC, bone areas and BMD follow different patterns in appendicular and axial bones.

Keywords: Dual-energy X-ray absorptiometry; bone mineral content; bone mineral density; regional; whole body

Conflict of interest statement

No financial support or competing financial interests in relation to this work.

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