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Emilsson ÖI, Hägg SA, Lindberg E, et al. Snoring and nocturnal reflux: association with lung function decline and respiratory symptoms. ERJ Open Res. 2019;5(2)doi: 10.1183/23120541.00010-2019.
Emilsson, �. �. I., Hägg, S. A., Lindberg, E., Franklin, K. A., Toren, K., Benediktsdottir, B., Aspelund, T., Gómez Real, F., Leynaert, B., Demoly, P., Sigsgaard, T., Perret, J., Malinovschi, A., Jarvis, D., Garcia-Aymerich, J., Gislason, T., & Janson, C. (2019). Snoring and nocturnal reflux: association with lung function decline and respiratory symptoms. ERJ open research, 5(2), . https://doi.org/10.1183/23120541.00010-2019
Emilsson, Össur Ingi, et al. "Snoring and nocturnal reflux: association with lung function decline and respiratory symptoms." ERJ open research vol. 5,2 (2019). doi: https://doi.org/10.1183/23120541.00010-2019
Emilsson ÖI, Hägg SA, Lindberg E, Franklin KA, Toren K, Benediktsdottir B, Aspelund T, Gómez Real F, Leynaert B, Demoly P, Sigsgaard T, Perret J, Malinovschi A, Jarvis D, Garcia-Aymerich J, Gislason T, Janson C. Snoring and nocturnal reflux: association with lung function decline and respiratory symptoms. ERJ Open Res. 2019 May 28;5(2). doi: 10.1183/23120541.00010-2019. eCollection 2019 Apr. PMID: 31149624; PMCID: PMC6536862.
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ERJ Open Res. 2019 May 28;5(2). doi: 10.1183/23120541.00010-2019. eCollection 2019 Apr.

Snoring and nocturnal reflux: association with lung function decline and respiratory symptoms.

ERJ open research

Össur Ingi Emilsson, Shadi Amid Hägg, Eva Lindberg, Karl A Franklin, Kjell Toren, Bryndis Benediktsdottir, Thor Aspelund, Francisco Gómez Real, Bénédicte Leynaert, Pascal Demoly, Torben Sigsgaard, Jennifer Perret, Andrei Malinovschi, Deborah Jarvis, Judith Garcia-Aymerich, Thorarinn Gislason, Christer Janson

Affiliations

  1. Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
  2. Respiratory Medicine and Allergology, Akademiska Sjukhuset, Uppsala, Sweden.
  3. Perioperative Sciences and Surgery, Dept of Surgery, Umeå University, Umeå, Sweden.
  4. Occupational and Environmental Medicine, University of Gothenburg, Gothenburg, Sweden.
  5. Dept of Sleep Medicine, Landspitali, Reykjavik, Iceland.
  6. Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  7. Centre for Public Health Sciences, University of Iceland, Reykjavik, Iceland.
  8. Dept of Clinical Science, University of Bergen, Bergen, Norway.
  9. Pathophysiology and Epidemiology of Respiratory Diseases, University of Paris, Paris, France.
  10. Dept of Pulmonology, Division of Allergy, Hôpital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France.
  11. Inserm, Sorbonne Université, Equipe EPAR - IPLESP, Paris, France.
  12. Institute of Public Health, Aarhus University, Aarhus, Denmark.
  13. Centre for Epidemiology and Biostatistics, University of Melbourne, Melbourne, Australia.
  14. Clinical Physiology, Uppsala University, Uppsala, Sweden.
  15. MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.
  16. ISGlobal, Center for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
  17. Pompeu Fabra University (UPF), Barcelona, Spain.
  18. CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.

PMID: 31149624 PMCID: PMC6536862 DOI: 10.1183/23120541.00010-2019

Abstract

INTRODUCTION: The study aim was to examine the association of snoring and nocturnal gastro-oesophageal reflux (nGOR) with respiratory symptoms and lung function, and if snoring and/or nGOR associated with a steeper decline in lung function.

METHODS: Data from the third visit of the European Community Respiratory Health Survey (ECRHS) was used for cross-sectional analysis. Pre- and post-bronchodilator spirometry was performed, and information on sleep, nGOR and respiratory symptoms was collected (n=5715). Habitual snoring and nGOR were assessed by questionnaire reports. Pre-bronchodilator spirometry from ECRHS I, II and III (20 years follow-up) were used to analyse lung function changes by multivariate regression analysis.

RESULTS: Snoring and nGOR were independently associated with a higher prevalence of wheeze, chest tightness, breathlessness, cough and phlegm. The prevalence of any respiratory symptom was 79% in subjects with both snoring and nGOR

CONCLUSIONS: Adults reporting both habitual snoring and nGOR had more respiratory symptoms and more frequent exacerbations of these symptoms. Habitual snoring was associated with a steeper decline in lung function over time.

Conflict of interest statement

Conflict of interest: Ö.I. Emilsson has nothing to disclose. Conflict of interest: S.A. Hägg has nothing to disclose. Conflict of interest: E. Lindberg has nothing to disclose. Conflict of interest: K

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