Display options
Share it on

Rev Bras Ortop. 2013 Aug 13;48(3):228-235. doi: 10.1016/j.rboe.2012.07.003. eCollection 2013.

Vitamin D and its Relation to Bone Mineral Density in Postmenopause Women.

Revista brasileira de ortopedia

Pedro José Labronici, Saulo Santos Blunck, Flavius Ribeiro Lana, Bruno Bandeira Esteves, José Sergio Franco, Junji Miller Fukuyama, Robinson Esteves Santos Pires

Affiliations

  1. PhD in Medicine at Escola Paulista de Medicina, at Universidade Federal de São Paulo; Clinical Head of the Orthopedics and Traumatology Service of Prof. Dr. Donato D'Ângelo, Hospital Santa Teresa, Petrópolis, RJ, Brazil.
  2. Resident Physician of the Orthopedics and Traumatology Service of Prof. Dr. Donato D'Ângelo, Hospital Santa Teresa, Petrópolis, RJ, Brazil.
  3. Head of Department, Associate Professor and Doctor of the Orthopedics and Traumatology Service of the Department of the Medical School at UFRJ, Rio de Janeiro, RJ, Brazil.
  4. Head of the Trauma Group of the Hospital Geral Vila Penteado, São Paulo, SP, Brazil.
  5. Assistant Professor of the Department of the Locomotor System of the Universidade Federal de Minas Gerais and Coordinator of the Specialization Course in Orthopedics and Traumatology of the Hospital Felício Rocho, Belo Horizonte, MG, Brazil.

PMID: 31214537 PMCID: PMC6565868 DOI: 10.1016/j.rboe.2012.07.003

Abstract

OBJECTIVE: Compare the level of vitamin D with the bone mineral density (BMD) in postmenopausal women, with or without fractures.

METHODS: 250 women with mean age of 71.1 were evaluated. The serum levels of vitamin D considered sufficient were ≥ 30 ng/mL, insufficient between 20 and 30 ng/mL and deficient < 20 ng/mL. The bone mineral density was measured and considered osteopenia when T value total of lumbar spine or hip was between -1 and -2.5 and osteoporosis < 2.5. The patients with fractures accounted for 25.2%.

RESULTS: There was no significant difference in the vitamin D (ng/mL) levels among the age groups (p = 0.25), the levels of fractures (p = 0.79) and the levels of BMD (p = 0.76).

CONCLUSION: 82% of the patients presented deficient and insufficient blood levels of vitamin D. Ours results showed any significant correlation between vitamin D levels and bone mineral density after adjusting for age.

Keywords: Bone density; Fractures bone; Osteoporosis; Vitamin D

References

  1. Calcif Tissue Int. 1999 Jul;65(1):23-8 - PubMed
  2. Bone. 2001 Nov;29(5):428-30 - PubMed
  3. J Am Coll Nutr. 2003 Apr;22(2):142-6 - PubMed
  4. Am J Med. 1992 Jul;93(1):69-77 - PubMed
  5. Am J Med. 2004 May 1;116(9):634-9 - PubMed
  6. Endocrine. 2004 Jun;24(1):47-53 - PubMed
  7. Osteoporos Int. 2005 Dec;16(12):1649-54 - PubMed
  8. Bone. 2007 Mar;40(3):716-22 - PubMed
  9. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):614-9 - PubMed
  10. J Clin Endocrinol Metab. 2007 Jun;92(6):2130-5 - PubMed
  11. Arq Bras Endocrinol Metabol. 2007 Apr;51(3):437-42 - PubMed
  12. Am J Epidemiol. 2007 Dec 1;166(11):1327-36 - PubMed
  13. J Bone Miner Metab. 2008;26(1):86-92 - PubMed
  14. Semin Arthritis Rheum. 2009 Jun;38(6):444-51 - PubMed
  15. Endocrine. 2008 Feb;33(1):95-100 - PubMed
  16. J Bone Miner Res. 2008 Nov;23(11):1859-63 - PubMed
  17. Am J Clin Nutr. 2008 Aug;88(2):558S-564S - PubMed
  18. Osteoporos Int. 2009 Nov;20(11):1807-20 - PubMed
  19. J Bone Joint Surg Br. 2010 Apr;92(4):496-9 - PubMed
  20. Bone. 2010 Aug;47(2):400-7 - PubMed
  21. Arq Bras Endocrinol Metabol. 2010 Mar;54(2):227-32 - PubMed
  22. J Bone Joint Surg Am. 2010 Oct 6;92(13):2300-4 - PubMed
  23. Ann Saudi Med. 2011 Nov-Dec;31(6):602-8 - PubMed
  24. J Am Acad Orthop Surg. 2012 Mar;20(3):123-9 - PubMed
  25. Gerontology. 1990;36(1):55-8 - PubMed
  26. J Am Geriatr Soc. 1989 Jul;37(7):589-92 - PubMed
  27. Am J Clin Nutr. 1987 Apr;45(4):755-63 - PubMed
  28. JAMA. 1995 Dec 6;274(21):1683-6 - PubMed
  29. N Engl J Med. 1994 Sep 29;331(13):821-7 - PubMed
  30. Osteoporos Int. 1994 Jan;4(1):6-10 - PubMed
  31. Am J Epidemiol. 1994 Mar 1;139(5):493-503 - PubMed
  32. N Engl J Med. 1994 Jun 2;330(22):1555-9 - PubMed
  33. J Bone Miner Res. 1997 Sep;12(9):1321-9 - PubMed
  34. N Engl J Med. 1998 Mar 19;338(12):777-83 - PubMed
  35. J Bone Miner Res. 1998 Jul;13(7):1167-74 - PubMed
  36. N Engl J Med. 1998 Sep 10;339(11):733-8 - PubMed

Publication Types