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Honkanen M, Jämsen E, Karppelin M, et al. Periprosthetic Joint Infections as a Consequence of Bacteremia. Open Forum Infect Dis. 2019;6(6):ofz218doi: 10.1093/ofid/ofz218.
Honkanen, M., Jämsen, E., Karppelin, M., Huttunen, R., Eskelinen, A., & Syrjänen, J. (2019). Periprosthetic Joint Infections as a Consequence of Bacteremia. Open forum infectious diseases, 6(6), ofz218. https://doi.org/10.1093/ofid/ofz218
Honkanen, Meeri, et al. "Periprosthetic Joint Infections as a Consequence of Bacteremia." Open forum infectious diseases vol. 6,6 (2019): ofz218. doi: https://doi.org/10.1093/ofid/ofz218
Honkanen M, Jämsen E, Karppelin M, Huttunen R, Eskelinen A, Syrjänen J. Periprosthetic Joint Infections as a Consequence of Bacteremia. Open Forum Infect Dis. 2019 May 07;6(6):ofz218. doi: 10.1093/ofid/ofz218. eCollection 2019 Jun. PMID: 31214625; PMCID: PMC6565379.
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Open Forum Infect Dis. 2019 May 07;6(6):ofz218. doi: 10.1093/ofid/ofz218. eCollection 2019 Jun.

Periprosthetic Joint Infections as a Consequence of Bacteremia.

Open forum infectious diseases

Meeri Honkanen, Esa Jämsen, Matti Karppelin, Reetta Huttunen, Antti Eskelinen, Jaana Syrjänen

Affiliations

  1. Department of Internal Medicine, Tampere University Hospital, Tampere University, Tampere, Finland.
  2. Coxa Hospital for Joint Replacement, Tampere and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

PMID: 31214625 PMCID: PMC6565379 DOI: 10.1093/ofid/ofz218

Abstract

BACKGROUND: The risk for developing a periprosthetic joint infection (PJI) during bacteremia is unclear, except for

METHODS: Patients with a primary knee or hip joint replacement performed in a tertiary care hospital between September 2002 and December 2013 were identified (n = 14 378) and followed up until December 2014. Positive blood culture results during the study period and PJIs were recorded. PJIs associated with an episode of bacteremia were identified and confirmed from patient records. Potential risk factors for PJI among those with bacteremia were examined using univariate logistic regression.

RESULTS: A total of 542 (3.8%) patients had at least 1 episode of bacteremia. Seven percent (47/643) of the bacteremias resulted in a PJI. Development of a PJI was most common for

CONCLUSIONS: The development of a PJI during bacteremia depends on the pathogen causing the bacteremia and the timing of bacteremia with respect to previous joint replacement surgery. However, significant patient-related risk factors for PJI during bacteremia could not be found.

Keywords: Staphylococcus aureus; bacteremia; prosthetic joint infection; risk factors; streptococci

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