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Sarda C, Magrini G, Pelenghi S, et al. Mitral Valve Infective Endocarditis due to Streptococcus pyogenes: A Case Report. Cureus. 2019;11(4):e4461doi: 10.7759/cureus.4461.
Sarda, C., Magrini, G., Pelenghi, S., Turco, A., & Seminari, E. (2019). Mitral Valve Infective Endocarditis due to Streptococcus pyogenes: A Case Report. Cureus, 11(4), e4461. https://doi.org/10.7759/cureus.4461
Sarda, Cristina, et al. "Mitral Valve Infective Endocarditis due to Streptococcus pyogenes: A Case Report." Cureus vol. 11,4 (2019): e4461. doi: https://doi.org/10.7759/cureus.4461
Sarda C, Magrini G, Pelenghi S, Turco A, Seminari E. Mitral Valve Infective Endocarditis due to Streptococcus pyogenes: A Case Report. Cureus. 2019 Apr 15;11(4):e4461. doi: 10.7759/cureus.4461. PMID: 31249739; PMCID: PMC6579330.
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Cureus. 2019 Apr 15;11(4):e4461. doi: 10.7759/cureus.4461.

Mitral Valve Infective Endocarditis due to Streptococcus pyogenes: A Case Report.

Cureus

Cristina Sarda, Giulia Magrini, Sfefano Pelenghi, Annalisa Turco, Elena Seminari

Affiliations

  1. Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, Pavia, ITA.
  2. Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia , ITA.
  3. Cardiac Surgery, Fondazione IRCCS Policlinico San Matteo, Pavia, ITA.
  4. Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, ITA.
  5. Infectious Diseses, Fondazione IRCCS Policlinico San Matteo, Pavia, ITA.

PMID: 31249739 PMCID: PMC6579330 DOI: 10.7759/cureus.4461

Abstract

Infective endocarditis (IE) due to group A β-hemolytic streptococcus (Streptococcus pyogenes) has rarely been reported in the literature. We herein report a Streptococcus pyogenes native mitral valve endocarditis in a young patient and a review of the literature. The patient had a native mitral valve endocarditis with vegetation; his hemodynamic stability and a short course of antibiotic treatment prevented urgent surgery on the mitral valve. He was previously treated with cefixime and azithromycin for four days and then, upon hospital admission, with vancomycin plus amoxicillin-clavulanate. After the diagnosis of IE due to Streptococcus pyogenes, treatment with gentamicin (3 mg/kg daily) and ampicillin (12 g/day) was implemented. The patient underwent weekly echocardiographic evaluations during antibiotic treatment to document the resolution of the vegetations. He was discharged to home in good clinical conditions after a four-week course of antibiotic treatment.

Keywords: infective endocarditis; streptococcus pyogenes

Conflict of interest statement

The authors have declared that no competing interests exist.

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