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Roa FJ, Peña E, Inostroza E, et al. Data on SVCT2 transporter expression and localization in cancer cell lines and tissues. Data Brief. 2019;25:103972doi: 10.1016/j.dib.2019.103972.
Roa, F. J., Peña, E., Inostroza, E., Sotomayor, K., González, M., Gutierrez-Castro, F. A., Maurin, M., Sweet, K., Labrousse, C., Gatica, M., Aylwin, C. F., Mendoza, P., Maldonado, M., Delgado, C., Madariaga, J., Panes, J., Silva-Grecchi, T., Concha, I. I., Moraga-Cid, G., Reyes, A. M., Muñoz-Montesino, C., Vera, J. C., & Rivas, C. I. (2019). Data on SVCT2 transporter expression and localization in cancer cell lines and tissues. Data in brief, 25103972. https://doi.org/10.1016/j.dib.2019.103972
Roa, Francisco J, et al. "Data on SVCT2 transporter expression and localization in cancer cell lines and tissues." Data in brief vol. 25 (2019): 103972. doi: https://doi.org/10.1016/j.dib.2019.103972
Roa FJ, Peña E, Inostroza E, Sotomayor K, González M, Gutierrez-Castro FA, Maurin M, Sweet K, Labrousse C, Gatica M, Aylwin CF, Mendoza P, Maldonado M, Delgado C, Madariaga J, Panes J, Silva-Grecchi T, Concha II, Moraga-Cid G, Reyes AM, Muñoz-Montesino C, Vera JC, Rivas CI. Data on SVCT2 transporter expression and localization in cancer cell lines and tissues. Data Brief. 2019 May 06;25:103972. doi: 10.1016/j.dib.2019.103972. eCollection 2019 Aug. PMID: 31249848; PMCID: PMC6586595.
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Data Brief. 2019 May 06;25:103972. doi: 10.1016/j.dib.2019.103972. eCollection 2019 Aug.

Data on SVCT2 transporter expression and localization in cancer cell lines and tissues.

Data in brief

Francisco J Roa, Eduardo Peña, Eveling Inostroza, Kirsty Sotomayor, Mauricio González, Francisco A Gutierrez-Castro, Michelle Maurin, Karen Sweet, Claire Labrousse, Marcell Gatica, Carlos F Aylwin, Pamela Mendoza, Mafalda Maldonado, Carolina Delgado, Jaime Madariaga, Jessica Panes, Tiare Silva-Grecchi, Ilona I Concha, Gustavo Moraga-Cid, Alejandro M Reyes, Carola Muñoz-Montesino, Juan Carlos Vera, Coralia I Rivas

Affiliations

  1. Departamento de Fisiopatología, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, PO Box 160C, Concepción, Chile.
  2. Departamento de Especialidades Médicas, Facultad de Medicina, Universidad de Concepción, Barrio Universitario s/n, PO Box 160C, Concepción, Chile.
  3. Departamento de Fisiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, PO Box 160C, Concepción, Chile.
  4. Instituto de Bioquímica y Microbiología, Facultad de Ciencias, Universidad Austral de Chile, Campus Isla Teja, PO Box 567, Valdivia, Chile.

PMID: 31249848 PMCID: PMC6586595 DOI: 10.1016/j.dib.2019.103972

Abstract

The data presented in this article are related to the research paper entitled "Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer", available in Free Radical Biology and Medicine Journal [1]. In this article, we examined the SVCT2 transporter expression in various breast cancer cell lines using RT-PCR and Western blot assays. In addition, we analyzed the subcellular localization of SVCT2 by immunofluorescence colocalization assays and cellular fractionation experiments. Finally, an analysis of different cancer tissue microarrays immunostained for SVCT2 and imaged by The Human Protein Atlas (https://www.proteinatlas.org) is presented.

References

  1. Nat Protoc. 2007;2(2):287-95 - PubMed
  2. Free Radic Biol Med. 2014 May;70:241-54 - PubMed
  3. Free Radic Biol Med. 2019 May 1;135:283-292 - PubMed

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