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J Vasc Bras. 2019 Jan 30;18:e20180021. doi: 10.1590/1677-5449.002118. eCollection 2019.

What has changed in venous thromboembolism prophylaxis for hospitalized patients over recent decades: review article.

Jornal vascular brasileiro

Selma Regina de Oliveira Raymundo, Suzana Margareth Ajeje Lobo, Kassim Mohamede Kassim Hussain, Kassim Guzzon Hussein, Isabela Tobal Secches

Affiliations

  1. Faculdade Regional de Medicina de São José do Rio Preto - FAMERP, Hospital de Base, São José do Rio Preto, SP, Brasil.
  2. Hospital Austa, São José do Rio Preto, SP, Brasil.
  3. Faculdade de Medicina em São José do Rio Preto - FACERES, São José do Rio Preto, SP, Brasil.

PMID: 31191626 PMCID: PMC6542320 DOI: 10.1590/1677-5449.002118

Abstract

Venous thromboembolism (VTE) is a common disease with high rates of morbidity and mortality and is considered the number one cause of avoidable mortality among hospitalized patients. Although VTE incidence is extremely high in all countries and there is ample evidence that thromboprophylaxis inexpensively reduces the rate of thromboembolic complications in both clinical and surgical patients, a great deal of doubt remains with respect to patient safety with this type of intervention and in relation to the ideal thromboprophylaxis methods. Countless studies and evidence-based recommendations confirm the efficacy of prophylaxis for prevention of VTE and/or patient deaths, but it remains underutilized to this day. This article presents a wide-ranging review of existing prophylaxis methods up to the present, from guidelines and national and international studies of thromboprophylaxis.

Keywords: anticoagulants; prevention & control; venous thromboembolism

Conflict of interest statement

Conflicts of interest: No conflicts of interest declared concerning the publication of this article.

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