Multidiscip Respir Med. 2019 Jul 01;14:22. doi: 10.1186/s40248-019-0184-5. eCollection 2019.
Role of blood glucose and fat profile in lung function pattern of Indian type 2 diabetic subjects.
Multidisciplinary respiratory medicine
Morteza A Khafaie, Sundeep S Salvi, Chittaranjan S Yajnik, Fakher Rahim, Behzad Khafaei
Affiliations
Affiliations
- 1Social Determinants of Health Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
- 2Department of Public Health, Faculty of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
- 3Chest Research Foundation (CRF), Pune, Maharashtra India.
- 4King Edward Memorial Hospital Research Center, Pune, Maharashtra India.
- 5Thalassemia and Hemoglobinopathy Research Centre, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
- Department of Statistics, Omidieh Branch, Islamic Azad University, Omidieh, Iran.
PMID: 31304013
PMCID: PMC6600883 DOI: 10.1186/s40248-019-0184-5
Abstract
BACKGROUND AND OBJECTIVES: It has been hypothesized that changes in lung function can occur in patients with diabetes. Nevertheless, it is unclear how much of this correlation links with biomarkers of metabolism disorder. We have investigated the association between hypoglycaemic and fat profile with lung function in Indian diabetic subjects.
DESIGN: Prospective observational study.
SETTING: Diabetes care unit of King Edward Memorial (KEM) hospital.
PATIENTS: Out of 465 patients who agreed to participate in this study, valid lung function data were available from 347 Type 2 diabetic subjects.
MEASUREMENTS: Pulmonary function test including predicted forced vital capacity (% FVC), predicted forced expiratory volume in 1 second (% FEV
RESULTS: Four hundred sixty-five subjects aged 55 ± 11 participated in the study. Predicted forced vital capacity, % FEV
CONCLUSIONS: It is difficult to draw a clear conclusion about the cause-effect relationship or clinical impact based on this study alone. However, identification of clinically meaningful elements for developing a screening program is critical.
Keywords: Diabetes mellitus; Fat profile; risk factors; Hyperglycaemia; Respiratory distress syndrome
Conflict of interest statement
Competing interestsThe authors declare that they have no competing interests. SS is member of the Editorial Board of Multidisciplinary Respiratory Medicine.
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