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Vijh R, O'Connell J, de Barra E, et al. Evolving chronic disease management in HIV care in an era of improved long-term survival. Ir J Med Sci. 2019;189(1):337-339doi: 10.1007/s11845-019-02063-y.
Vijh, R., O'Connell, J., de Barra, E., & McConkey, S. (2020). Evolving chronic disease management in HIV care in an era of improved long-term survival. Irish journal of medical science, 189(1), 337-339. https://doi.org/10.1007/s11845-019-02063-y
Vijh, Rohit, et al. "Evolving chronic disease management in HIV care in an era of improved long-term survival." Irish journal of medical science vol. 189,1 (2020): 337-339. doi: https://doi.org/10.1007/s11845-019-02063-y
Vijh R, O'Connell J, de Barra E, McConkey S. Evolving chronic disease management in HIV care in an era of improved long-term survival. Ir J Med Sci. 2020 Feb;189(1):337-339. doi: 10.1007/s11845-019-02063-y. Epub 2019 Jul 23. PMID: 31338690.
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Ir J Med Sci. 2020 Feb;189(1):337-339. doi: 10.1007/s11845-019-02063-y. Epub 2019 Jul 23.

Evolving chronic disease management in HIV care in an era of improved long-term survival.

Irish journal of medical science

Rohit Vijh, James O'Connell, Eoghan de Barra, Samuel McConkey

Affiliations

  1. School of Medicine, University of Toronto, Toronto, Canada.
  2. Royal College of Surgeons in Ireland, Dublin, Ireland. [email protected].
  3. Royal College of Surgeons in Ireland, Dublin, Ireland.
  4. Beaumont Hospital, Dublin, Ireland.

PMID: 31338690 DOI: 10.1007/s11845-019-02063-y

Abstract

BACKGROUND: Adults ageing with HIV and on antiretroviral therapy have a greater burden of chronic diseases compared with adults without HIV as reported by Althoff et al. (Curr Opin HIV AIDS 11:527-36, 2016). Therefore, it is important in this clinically stable HIV+ population to monitor and evaluate their risk of chronic kidney disease and intervene when appropriate. The European AIDS Clinical Society (EACS) advise that yearly screening for CKD with eGFR calculation and spot urine protein measurements should be performed (European AIDS Clinical Society Guidelines 2018). The Centre for Excellence for Health, Immunity and Infection (CHIP) have created a validated study calculator to estimate a patient's risk for CKD as reported by Mocroft et al. (PLoS Med 12(3):e1001809, 2015).

AIMS: (1) To determine the proportion of patients who had a urinary protein-creatinine ratio checked in 2018; (2) To calculate an eGFR for each patient in our cohort utilizing the Modification of Diet in Renal Disease (MDRD) calculation; (3) To calculate the full chronic kidney disease score in our cohort of patients.

METHODS: We undertook a retrospective chart review of 80 HIV-positive patients who attended our weekly clinic in Beaumont Hospital, Dublin, Ireland.

RESULTS: In our subset of 31 patients who had all the requirements to estimate their eGFR and full chronic kidney disease risk score, 100% (31/31) of eGFRs calculated were reported as > 90 mL/min/1.73 m

CONCLUSION: Although this audit was small and with limitations, it highlights the importance of collecting relevant and accurate patient data annually to estimate and mitigate the risk of chronic kidney disease in patients with HIV.

References

  1. Lancet HIV. 2019 Feb;6(2):e93-e104 - PubMed
  2. Adv Chronic Kidney Dis. 2010 Jan;17(1):19-25 - PubMed
  3. Curr Opin HIV AIDS. 2016 Sep;11(5):527-536 - PubMed
  4. Lancet. 2014 Jul 19;384(9939):241-8 - PubMed
  5. PLoS Med. 2015 Mar 31;12(3):e1001809 - PubMed

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