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Arafa WAA, Ibrahim HM. Sustainable and scalable synthesis of polysubstituted bis-1,2,4-triazoles, bis-2-iminothiazolines and bis-thiobarbiturates using bis-. R Soc Open Sci. 2019;6(6):181963doi: 10.1098/rsos.181963.
Arafa, W. A. A., & Ibrahim, H. M. (2019). Sustainable and scalable synthesis of polysubstituted bis-1,2,4-triazoles, bis-2-iminothiazolines and bis-thiobarbiturates using bis-. Royal Society open science, 6(6), 181963. https://doi.org/10.1098/rsos.181963
Arafa, Wael Abdelgayed Ahmed, and Ibrahim, Hamada Mohamed. "Sustainable and scalable synthesis of polysubstituted bis-1,2,4-triazoles, bis-2-iminothiazolines and bis-thiobarbiturates using bis-." Royal Society open science vol. 6,6 (2019): 181963. doi: https://doi.org/10.1098/rsos.181963
Arafa WAA, Ibrahim HM. Sustainable and scalable synthesis of polysubstituted bis-1,2,4-triazoles, bis-2-iminothiazolines and bis-thiobarbiturates using bis-. R Soc Open Sci. 2019 Jun 19;6(6):181963. doi: 10.1098/rsos.181963. eCollection 2019 Jun. PMID: 31312476; PMCID: PMC6599792.
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R Soc Open Sci. 2019 Jun 19;6(6):181963. doi: 10.1098/rsos.181963. eCollection 2019 Jun.

Sustainable and scalable synthesis of polysubstituted bis-1,2,4-triazoles, bis-2-iminothiazolines and bis-thiobarbiturates using bis-.

Royal Society open science

Wael Abdelgayed Ahmed Arafa, Hamada Mohamed Ibrahim

Affiliations

  1. Department of Chemistry, College of Science, Jouf University, PO Box 2014, Sakaka, Aljouf, Kingdom of Saudi Arabia.
  2. Department of Chemistry, Faculty of Science, Fayoum University, PO Box 63514 Fayoum City, Egypt.

PMID: 31312476 PMCID: PMC6599792 DOI: 10.1098/rsos.181963

Abstract

An expedient and tandem regioselective one-pot protocol for the sono-synthesis of bis-[1,2,4]-triazol-3-yl amines and bis-2-iminothiazolines from corresponding bis-1,3-disubstituted thioureas has been developed. The products' regioselectivity correlate well with the p

Keywords: bis-2-iminothiazolines; bis-[1,2,4]-triazol-3-yl amines; green metrics; regioselectivity; ultrasonic irradiation

Conflict of interest statement

We have no competing interests.

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