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Sudan J Paediatr. 2019;19(1):44-51. doi: 10.24911/SJP.106-1513711620.

Insight into potassium's role in childhood mortality due to severe acute malnutrition.

Sudanese journal of paediatrics

Sumia M S Alasad, Omaima Abdelmajeed Mohamed Salih, Mahmoud Hassan

Affiliations

  1. Departments of Pediatrics, Faculty of Medicine, Omdurman Islamic University, Omdurman, Sudan.
  2. Mohammed A Hamid's Pediatrics Hospital, Omdurman, Sudan.
  3. Swiss Tropical and Public Health Institute and University of Basel, Socinstrasse 59, 4001 Basel CH.

PMID: 31384088 PMCID: PMC6589795 DOI: 10.24911/SJP.106-1513711620

Abstract

Hypokalaemia is associated with an increase in mortality in children with severe acute malnutrition (SAM) and diarrhoea. This is a descriptive cross-sectional retrospective study conducted in the Nutritional Ward at Mohamed Alamin Hamid Pediatrics Hospital in Omdurman, Sudan. It aimed to assess the frequency of hypokalaemia among children with SAM to understand the influence of hypokalaemia and potassium supplementations contributed on the children survival rates (January-December 2015). It included 215 patients with SAM and acute diarrhoea. The potassium levels of all the patients were assessed upon hospital admission and this correlated with the mortality according to the degree of hypokalaemia and treatment initiated. Hypokalaemia was evident in 70.2% of the patients. Mortality was 3.1% in normokalaemic and 13.9% in hypokalaemic patients. The patients' survival was significantly associated with their serum potassium levels and the treatment received. The survival rates have been assessed via the Multinomial Logistic Model, which reveals that normokalaemic children had a chance of 157.349 (95% confidence interval 18.479-1,339.811) times higher than that compared to the baseline children with advanced hypokalaemia with serum levels <2 mEq/l (

Keywords: Hypokalaemia; I.V potassium; Mohamed Alamin Hamid Pediatric Hospital; Omdurman; Rehydration solution; Severe acute malnutrition; Sudan

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