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Biomed Opt Express. 2019 Jul 17;10(8):4050-4058. doi: 10.1364/BOE.10.004050. eCollection 2019 Aug 01.

Spectroscopic signature of the pathological processes of carious dentine based on FTIR investigations of the oral biological fluids.

Biomedical optics express

Pavel Seredin, Dmitry Goloshchapov, Yuri Ippolitov, Jitraporn Vongsvivut

Affiliations

  1. Department of Solid State Physics and Nanostructures, Voronezh State University, Voronezh, University Sq. 1, 394018, Russia.
  2. Ural Federal University, 19 Mira Street, Ekaterinburg, 620002, Russia.
  3. Department of Pediatric Dentistry with Orthodontia, Voronezh State Medical University, Voronezh, Studentcheskaya st. 11, 394006, Russia.
  4. Australian Synchrotron (Synchrotron Light Source Australia Pty LTD), 800 Blackburn Rd, Clayton, VIC 3168, Australia.

PMID: 31452994 PMCID: PMC6701548 DOI: 10.1364/BOE.10.004050

Abstract

The aim of our work is to find a spectroscopic signature of the pathological processes of carious dentine based on the investigations of the molecular composition of the oral biological fluids with the use of FTIR synchrotron techniques. This complex analysis of the obtained data shows that a number of signatures are present only in the spectra of dentine and gingival fluids from the patients developing caries of the deep dentine tissues. The detected features and complex analysis of the quantitative and qualitative data representing signatures of the development of oral cavity pathologies can enhance the quality of dental screening.

Conflict of interest statement

The authors declare that there are no conflicts of interest related to this article.

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