Display options
Cite
Alexander MS, O'Leary BR, Moose D, et al. A model for the detection of pancreatic ductal adenocarcinoma circulating tumor cells. J Biol Methods. 2018;5(3):e97doi: 10.14440/jbm.2018.250.
Alexander, M. S., O'Leary, B. R., Moose, D., Du, J., Henry, M. D., & Cullen, J. J. (2018). A model for the detection of pancreatic ductal adenocarcinoma circulating tumor cells. Journal of biological methods, 5(3), e97. https://doi.org/10.14440/jbm.2018.250
Alexander, Matthew S, et al. "A model for the detection of pancreatic ductal adenocarcinoma circulating tumor cells." Journal of biological methods vol. 5,3 (2018): e97. doi: https://doi.org/10.14440/jbm.2018.250
Alexander MS, O'Leary BR, Moose D, Du J, Henry MD, Cullen JJ. A model for the detection of pancreatic ductal adenocarcinoma circulating tumor cells. J Biol Methods. 2018 Sep 05;5(3):e97. doi: 10.14440/jbm.2018.250. eCollection 2018. PMID: 31453247; PMCID: PMC6706145.
Copy Download .nbib Format: NLM
Share it on

J Biol Methods. 2018 Sep 05;5(3):e97. doi: 10.14440/jbm.2018.250. eCollection 2018.

A model for the detection of pancreatic ductal adenocarcinoma circulating tumor cells.

Journal of biological methods

Matthew S Alexander, Brianne R O'Leary, Devon Moose, Juan Du, Michael D Henry, Joseph J Cullen

Affiliations

  1. Departments of Surgery, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
  2. Departments of Molecular Physiology and Biophysics, Pathology and Urology, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
  3. Holden Comprehensive Cancer Center, Iowa City, IA 52242, USA.
  4. Departments of Radiation Oncology, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
  5. Veterans Affairs Medical Center, Iowa City, IA 52246, USA.

PMID: 31453247 PMCID: PMC6706145 DOI: 10.14440/jbm.2018.250

Abstract

Metastatic disease is the leading cause of pancreatic ductal adenocarcinoma (PDAC) associated death. PDAC cells invade and enter the bloodstream early, before frank malignancy can be detected. Our objective was to develop an

Keywords: bioluminescent imaging; circulating tumor cells; metastasis; orthotopic implantation; pancreatic adenocarcinoma

Conflict of interest statement

Competing interests: The authors have declared that no competing interests exist.

References

  1. N Engl J Med. 2004 Mar 18;350(12):1200-10 - PubMed
  2. N Engl J Med. 2004 Aug 19;351(8):781-91 - PubMed
  3. JAMA. 2007 Jan 17;297(3):267-77 - PubMed
  4. Lancet Oncol. 2007 May;8(5):444-8 - PubMed
  5. J Gastrointest Surg. 2009 Apr;13(4):752-9 - PubMed
  6. Lancet Oncol. 2009 Mar;10(3):233-9 - PubMed
  7. Ann Oncol. 2009 Jul;20(7):1223-9 - PubMed
  8. Curr Opin Genet Dev. 2010 Feb;20(1):96-9 - PubMed
  9. Mol Cancer Res. 2011 Jul;9(7):867-77 - PubMed
  10. J Thorac Oncol. 2012 Mar;7(3):512-9 - PubMed
  11. Cell. 2012 Jan 20;148(1-2):349-61 - PubMed
  12. Cell. 2012 Jan 20;148(1-2):362-75 - PubMed
  13. Cancer Discov. 2012 Dec;2(12):1091-9 - PubMed
  14. Tumour Biol. 2014 Mar;35(3):2473-80 - PubMed
  15. J Gastrointest Cancer. 2014 Dec;45 Suppl 1:222-5 - PubMed
  16. Nat Rev Cancer. 2014 Sep;14(9):623-31 - PubMed
  17. Pancreas. 2015 May;44(4):547-50 - PubMed
  18. Cancer Res. 2015 Aug 15;75(16):3314-26 - PubMed
  19. Nature. 2015 Nov 26;527(7579):525-530 - PubMed
  20. Ann Surg. 2016 Dec;264(6):1073-1081 - PubMed
  21. Br J Cancer. 2016 Jun 14;114(12):1367-75 - PubMed
  22. Sci Rep. 2016 Jul 14;6:29736 - PubMed
  23. Discov Med. 2016 Sep;22(120):121-128 - PubMed
  24. Sci Rep. 2017 Jul 3;7(1):4510 - PubMed

Publication Types

Grant support