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El-Badry AA, El Sayed SS, Hussein RR, et al. Intestinal parasitism in pediatric oncology children receiving chemotherapy: unexpected low prevalence. Heliyon. 2019;5(8):e02228doi: 10.1016/j.heliyon.2019.e02228.
El-Badry, A. A., El Sayed, S. S., Hussein, R. R., Said, Y. M., Al-Antably, A. S., & Hassan, M. A. (2019). Intestinal parasitism in pediatric oncology children receiving chemotherapy: unexpected low prevalence. Heliyon, 5(8), e02228. https://doi.org/10.1016/j.heliyon.2019.e02228
El-Badry, Ayman A, et al. "Intestinal parasitism in pediatric oncology children receiving chemotherapy: unexpected low prevalence." Heliyon vol. 5,8 (2019): e02228. doi: https://doi.org/10.1016/j.heliyon.2019.e02228
El-Badry AA, El Sayed SS, Hussein RR, Said YM, Al-Antably AS, Hassan MA. Intestinal parasitism in pediatric oncology children receiving chemotherapy: unexpected low prevalence. Heliyon. 2019 Aug 12;5(8):e02228. doi: 10.1016/j.heliyon.2019.e02228. eCollection 2019 Aug. PMID: 31453397; PMCID: PMC6702426.
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Heliyon. 2019 Aug 12;5(8):e02228. doi: 10.1016/j.heliyon.2019.e02228. eCollection 2019 Aug.

Intestinal parasitism in pediatric oncology children receiving chemotherapy: unexpected low prevalence.

Heliyon

Ayman A El-Badry, Samar S El Sayed, Rafiaa R Hussein, Youssef M Said, Abeer S Al-Antably, Marwa A Hassan

Affiliations

  1. Department of Microbiology-Medical Parasitology Section, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
  2. Department of Parasitology, Faculty of Medicine for Girls, Al-Azhar University, Egypt.
  3. Paediatric Oncology Medicine, National Cancer Institute, Cairo University, Egypt.
  4. Department of Medical Parasitology, Kasr Al-Ainy School of Medicine, Cairo University, Egypt.

PMID: 31453397 PMCID: PMC6702426 DOI: 10.1016/j.heliyon.2019.e02228

Abstract

BACKGROUND: Children with underlying malignancies and those on chemotherapy are at risk for having intestinal parasitic infections, which can lead to a severe course and death. This cross-sectional study was done to assess the copro-parasitological and copro-molecular prevalence of entero-parasites in children with malignancies and those on chemotherapy.

PROCEDURE: Stool samples were collected from 137 Egyptian hospitalized cancerous children with different malignancies in the National Cancer Institute, and receiving chemotherapy.Faecal samples were examined microscopically. Genomic copro-DNA was extracted from fecal samples and amplified by 3 separate nPCR assays targeting

RESULT: The overall prevalence of enteroparasites was 6.6 % (9 cases). Only

CONCLUSION: Low prevalence may be due to patient's use of prophylactic anti-parasitic and anti-fungal drugs, a standard protocol, basic hygienic practices and good nursing all of which are preventive against enteroparasites transmission. Among studied variables only diarrhoeic individuals who had a solid tumor, and soft/liquid stool with mucus and blood were predictors of intestinal parasitism.

Keywords: Chemotherapy; Children; Egypt; Infectious disease; Intestinal parasites; Oncology; Parasitology; Pediatrics; Protozoa; Tumor

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