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Kicera-Temple K, Londoño L, Lanaux TM, et al. Treatment of a massive naproxen overdose with therapeutic plasma exchange in a dog. Clin Case Rep. 2019;7(8):1529-1533doi: 10.1002/ccr3.2277.
Kicera-Temple, K., Londoño, L., Lanaux, T. M., & Buckley, G. J. (2019). Treatment of a massive naproxen overdose with therapeutic plasma exchange in a dog. Clinical case reports, 7(8), 1529-1533. https://doi.org/10.1002/ccr3.2277
Kicera-Temple, Kathleen, et al. "Treatment of a massive naproxen overdose with therapeutic plasma exchange in a dog." Clinical case reports vol. 7,8 (2019): 1529-1533. doi: https://doi.org/10.1002/ccr3.2277
Kicera-Temple K, Londoño L, Lanaux TM, Buckley GJ. Treatment of a massive naproxen overdose with therapeutic plasma exchange in a dog. Clin Case Rep. 2019 Jun 28;7(8):1529-1533. doi: 10.1002/ccr3.2277. eCollection 2019 Aug. PMID: 31428382; PMCID: PMC6692984.
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Clin Case Rep. 2019 Jun 28;7(8):1529-1533. doi: 10.1002/ccr3.2277. eCollection 2019 Aug.

Treatment of a massive naproxen overdose with therapeutic plasma exchange in a dog.

Clinical case reports

Kathleen Kicera-Temple, Leonel Londoño, Travis M Lanaux, Gareth J Buckley

Affiliations

  1. Department of Small Animal Clinical Sciences University of Florida Gainesville Florida USA.

PMID: 31428382 PMCID: PMC6692984 DOI: 10.1002/ccr3.2277

Abstract

In comparison with other over-the-counter anti-inflammatory drugs, naproxen has a longer half-life in dogs and can lead to severe morbidity and mortality. This report describes the successful use of membrane-based therapeutic plasma exchange after a massive ingestion of naproxen by a dog resulting in 86% reduction in plasma concentration.

Keywords: acute kidney injury; non‐steroidal anti‐inflammatory drugs; therapeutic plasma exchange; toxicity

Conflict of interest statement

The authors report no conflicts of interest for this case report.

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