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Laitinen MK, Stevenson JD, Evans S, et al. Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases. J Bone Oncol. 2019;17:100248doi: 10.1016/j.jbo.2019.100248.
Laitinen, M. K., Stevenson, J. D., Evans, S., Abudu, A., Sumathi, V., Jeys, L. M., & Parry, M. C. (2019). Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases. Journal of bone oncology, 17100248. https://doi.org/10.1016/j.jbo.2019.100248
Laitinen, M K, et al. "Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases." Journal of bone oncology vol. 17 (2019): 100248. doi: https://doi.org/10.1016/j.jbo.2019.100248
Laitinen MK, Stevenson JD, Evans S, Abudu A, Sumathi V, Jeys LM, Parry MC. Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases. J Bone Oncol. 2019 Jun 27;17:100248. doi: 10.1016/j.jbo.2019.100248. eCollection 2019 Aug. PMID: 31428555; PMCID: PMC6695276.
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J Bone Oncol. 2019 Jun 27;17:100248. doi: 10.1016/j.jbo.2019.100248. eCollection 2019 Aug.

Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases.

Journal of bone oncology

M K Laitinen, J D Stevenson, S Evans, A Abudu, V Sumathi, L M Jeys, M C Parry

Affiliations

  1. Department of Orthopaedics and Traumatology, Helsinki University Hospital, Topeliuksenkatu 5, 00260 Helsinki, Finland.
  2. Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland.
  3. Oncology Department, Royal Orthopaedic Hospital, Bristol Road, Birmingham B31 2AP, UK.
  4. Aston University Medical School, Aston Expressway, Birmingham B4 7ET, UK.

PMID: 31428555 PMCID: PMC6695276 DOI: 10.1016/j.jbo.2019.100248

Abstract

INTRODUCTION: Chondroblastoma is a rare benign bone tumour that usually occurs in children and young adults. They are cartilaginous tumours arising in the epiphysis or apophysis of a long bone. The tumour is classified as benign, although rare cases of pulmonary metastases have been reported. The aims of this study were to describe clinical, radiographic characteristics of chondroblastoma; to analyse the local recurrence rate and complications associated with surgery.

MATERIAL AND METHODS: This retrospective study included 177 patients, who had been diagnosed with a chondroblastoma in extremity between 1990 and 2015.

RESULTS: The most common site was proximal tibia 20%, followed by proximal humerus 19%, proximal femur 18%, distal femur 16% and foot 15%. One patient has died of the disease and one patient is alive after being operated for lung metastases. There was local recurrence in 25/177 (14%) patients. The median time to local recurrence was 10 months (range 3-158 months). The most common site for local recurrence was proximal tibia (22.2%). The proximal femur was the location in 32/178 (18%) of the cases. 18/32 (56%) were in the greater trochanter and 14/32 (44%) in the femoral head. The mean age was lower in tumours located in femoral head when compared to the greater trochanter; 19.5 years and 13.9 years respectively (

CONCLUSIONS: Chondroblastoma is a rare benign to intermediate grade bone tumour with a potential to metastasise. Femoral head chondroblastoma is rare, presenting 4.5% of all chondroblastoma cases. Around 50% of the chondroblastoma in femoral head. occur in patients with open growth plates.

Keywords: Bone neoplasm; Chondroblastoma; Femur head; Growth plate

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