Open Access Maced J Med Sci. 2019 Jul 13;7(13):2127-2132. doi: 10.3889/oamjms.2019.606. eCollection 2019 Jul 15.
Echocardiographic Parameters Correlated with Age in Isolated Severe Rheumatic Mitral Stenosis Patients in Indonesia.
Open access Macedonian journal of medical sciences
Luh Oliva Saraswati Suastika, Amiliana Mardiani Soesanto
Affiliations
Affiliations
- Department of Cardiology and Vascular Medicine, Faculty of Medicine, Udayana University, Denpasar, Bali, Indonesia.
- Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center of Harapan Kita, Jakarta, Indonesia.
PMID: 31456838
PMCID: PMC6698102 DOI: 10.3889/oamjms.2019.606
Abstract
BACKGROUND: Despite the high prevalence of rheumatic mitral stenosis (MS) in Indonesia, the impact of aging on the anatomical and hemodynamic component of rheumatic MS is not well studied.
AIM: To analyze the association of age with various echocardiographic parameters in patients with isolated severe rheumatic MS in Indonesia.
METHODS: A cross-sectional study was conducted enrolling 263 subjects with isolated severe rheumatic MS who underwent transthoracic echocardiography (TTE) during January 2015 until December 2017 at National Cardiovascular Center of Harapan Kita, Jakarta, Indonesia. Demographic data were collected, and echocardiographic variables were measured based on standard TTE examination using GE Vivid 7 and S6 Doppler Echocardiography System (GE Medical System, Norway).
RESULTS: Of 263 subjects, there are 84 men and 179 women aged 18-80 (mean age 42.9) years old. Most patients had atrial fibrillation (80%), with a higher prevalence of AF in the older group. Age was positively correlated with LA diameter and Wilkin's score (r = 0.186, P = 0.002; r = 0.142, P = 0.022; respectively); while mean MVG (r = -0.304, P < 0.001), TR Vmax (r = -0.126, P = 0.04), TR maxPG (r = -0.127, P = 0.039) and TAPSE (r = -0.125, P = 0.044) were correlated negatively with age. Mean MVG has the strongest correlation with age in our subjects.
CONCLUSION: This is the first study in Indonesia that analyze the association of age and different echocardiographic parameters in isolated severe rheumatic severe MS patients. Age has a significant correlation with mean MVG, LA diameter, Wilkin's score, TR Vmax, TR maxPG, and TAPSE. We assume that the association of age and these parameters were influenced by the normal aging process and progression of chronic MS.
Keywords: Age; Echocardiography; Mitral stenosis; Rheumatic heart disease
References
- Am J Cardiol. 2000 Sep 1;86(5):529-34 - PubMed
- Br Heart J. 1975 Jan;37(1):26-36 - PubMed
- Eur J Echocardiogr. 2003 Mar;4(1):36-42 - PubMed
- Eur Heart J. 2003 Jul;24(13):1231-43 - PubMed
- Am J Cardiol. 1962 Dec;10:773-84 - PubMed
- Circulation. 2004 Feb 17;109(6):e38-41 - PubMed
- Lancet Infect Dis. 2005 Nov;5(11):685-94 - PubMed
- J Am Coll Cardiol. 2006 Jun 20;47(12):2357-63 - PubMed
- J Am Soc Echocardiogr. 2006 Jul;19(7):911-3 - PubMed
- J Am Soc Echocardiogr. 2009 Jan;22(1):1-23; quiz 101-2 - PubMed
- J Am Soc Echocardiogr. 2010 Jul;23(7):685-713; quiz 786-8 - PubMed
- Heart Fail Clin. 2012 Jan;8(1):143-64 - PubMed
- Arch Cardiovasc Dis. 2013 Feb;106(2):111-5 - PubMed
- J Am Coll Cardiol. 2014 Jun 10;63(22):2438-88 - PubMed
- Circ Res. 2014 Apr 25;114(9):1453-68 - PubMed
- J Am Soc Echocardiogr. 2014 Oct;27(10):1079-1086.e1 - PubMed
- J Am Soc Echocardiogr. 2015 Jan;28(1):1-39.e14 - PubMed
- Int J Cardiovasc Imaging. 2015 Apr;31(4):735-42 - PubMed
- J Am Soc Echocardiogr. 2016 May;29(5):461-9 - PubMed
- J Am Soc Echocardiogr. 2017 Apr;30(4):303-371 - PubMed
- Heart. 2017 Nov;103(21):1696-1703 - PubMed
- Eur Heart J. 2017 Sep 21;38(36):2739-2791 - PubMed
- J Am Heart Assoc. 2019 Mar 5;8(5):e010736 - PubMed
- Circulation. 1984 Oct;70(4):657-62 - PubMed
- J Heart Valve Dis. 1997 Nov;6(6):599-603 - PubMed
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