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ACS Omega. 2016 Oct 17;1(4):600-612. doi: 10.1021/acsomega.6b00142. eCollection 2016 Oct 31.

Glycopolypeptide-Grafted Bioactive Polyionic Complex Vesicles (PICsomes) and Their Specific Polyvalent Interactions.

ACS omega

Bhawana Pandey, Jaladhar Mahato, Karishma Berta Cotta, Soumen Das, Dharmendar Kumar Sharma, Sayam Sen Gupta, Arindam Chowdhury

Affiliations

  1. Chemical Engineering Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411008, India.
  2. Academy of Scientific and Innovative Research, (AcSIR), New Delhi 110 025, India.
  3. Department of Chemistry and Center for Research in Nanotechnology and Science, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.

PMID: 31457149 PMCID: PMC6640804 DOI: 10.1021/acsomega.6b00142

Abstract

Glycopolypeptide-based self-assembled nano-/microstructures with surface-tethered carbohydrates are excellent mimics of glycoproteins on the cell surface. To expand the broad repertoire of glycopolypeptide-based supramolecular soft structures such as polymersomes formed via self-assembly of amphiphilic polymers, we have developed a new class of polyionic complex vesicles (PICsomes) with glycopolypeptides grafted on the external surface. Oppositely charged hydrophilic block copolymers of glycopolypeptide

Conflict of interest statement

The authors declare no competing financial interest.

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