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Rajan ST, Narasimhan M, Rao KB, et al. Toxicity of xylene in occupationally exposed workers: A high-performance liquid chromatography analysis. J Oral Maxillofac Pathol. 2019;23(2):303doi: 10.4103/jomfp.JOMFP_297_18.
Rajan, S. T., Narasimhan, M., Rao, K. B., & Jacob, T. E. (2019). Toxicity of xylene in occupationally exposed workers: A high-performance liquid chromatography analysis. Journal of oral and maxillofacial pathology : JOMFP, 23(2), 303. https://doi.org/10.4103/jomfp.JOMFP_297_18
Rajan, Sharada T, et al. "Toxicity of xylene in occupationally exposed workers: A high-performance liquid chromatography analysis." Journal of oral and maxillofacial pathology : JOMFP vol. 23,2 (2019): 303. doi: https://doi.org/10.4103/jomfp.JOMFP_297_18
Rajan ST, Narasimhan M, Rao KB, Jacob TE. Toxicity of xylene in occupationally exposed workers: A high-performance liquid chromatography analysis. J Oral Maxillofac Pathol. 2019 May-Aug;23(2):303. doi: 10.4103/jomfp.JOMFP_297_18. PMID: 31516245; PMCID: PMC6714242.
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J Oral Maxillofac Pathol. 2019 May-Aug;23(2):303. doi: 10.4103/jomfp.JOMFP_297_18.

Toxicity of xylene in occupationally exposed workers: A high-performance liquid chromatography analysis.

Journal of oral and maxillofacial pathology : JOMFP

Sharada T Rajan, Malathi Narasimhan, K Bharath Rao, Tina Elizabeth Jacob

Affiliations

  1. Department of Oral Pathology, Faculty of Dental Sciences, SRIHER, Chennai, Tamil Nadu, India.
  2. Department of Oral Biology, Faculty of Dentistry, Melaka Manipal Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

PMID: 31516245 PMCID: PMC6714242 DOI: 10.4103/jomfp.JOMFP_297_18

Abstract

BACKGROUND: Xylene is one of the most commonly used solvents in industrial and medical technologies. Several health hazards of xylene have been documented in literature. Workers in certain forces appear to have the greatest potential for exposure to high concentrations of xylene - histopathology technicians and painters are two such groups. This study was undertaken with the aim to determine the level of xylene exposure and the various systemic health effects among these groups.

METHODOLOGY: The study was performed by analyzing the urine samples of the participants for methylhippuric acid, the established biomarker of xylene with the aid of high-performance liquid chromatography.

RESULTS AND CONCLUSION: The work hours per week of the occupationally exposed participants were statistically analyzed with that of the excretory values of the metabolites of xylene, and the

Keywords: Biomarker; methylhippuric acid; occupational hazard; toxicity study

Conflict of interest statement

There are no conflicts of interest.

References

  1. J Chromatogr B Biomed Sci Appl. 1999 Feb 19;723(1-2):95-104 - PubMed
  2. Toxicol Appl Pharmacol. 1975 Sep;33(3):543-58 - PubMed
  3. J Biochem Mol Toxicol. 2003;17(2):92-4 - PubMed
  4. Ind Med Surg. 1960 Jan;29:33-5 - PubMed
  5. J Clin Diagn Res. 2014 Feb;8(2):271-4 - PubMed
  6. IMS Ind Med Surg. 1970 May;39(5):215-20 - PubMed
  7. Arch Toxicol. 1980 Jul;45(2):117-22 - PubMed
  8. Int Arch Occup Environ Health. 1993;64(8):597-605 - PubMed
  9. Contact Dermatitis. 1993 Jan;28(1):44 - PubMed
  10. Int Arch Occup Environ Health. 1993;64(7):533-9 - PubMed
  11. Int Arch Occup Environ Health. 1977 Aug 31;39(3):181-9 - PubMed

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