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J Laryngol Otol. 2019 Sep;133(9):810-813. doi: 10.1017/S0022215119001683. Epub 2019 Aug 22.

Evaluation of serum ischaemia-modified albumin levels in patients with Bell's palsy.

The Journal of laryngology and otology

A E Göker, M H Alagöz, G Güntaş, A Baskadem Yilmazer, G Berkiten, B Tutar, M E Ekincioglu, M F Akgun, Y Uyar, E Ozdemir

Affiliations

  1. Department of Otorhinolaryngology - Head and Neck Surgery, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey.
  2. Department of Biochemistry, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey.
  3. School of Health, Kirklareli University, Kirklareli, Turkey.

PMID: 31434591 DOI: 10.1017/S0022215119001683

Abstract

OBJECTIVE: This prospective study aimed to evaluate the relationship between serum ischaemia-modified albumin levels and Bell's palsy severity.

METHODS: The study included 30 patients diagnosed with Bell's palsy and 30 healthy individuals. The patients were separated into three disease severity groups (grades 2, 3 and 4) according to House-Brackmann classification. Blood samples were collected from all participants and the results compared between groups.

RESULTS: Significant differences in serum ischaemia-modified albumin were found between the study and control groups (p < 0.001); values were significantly higher in the study group than in the control group.

CONCLUSION: The significantly higher levels of serum ischaemia-modified albumin in the study group suggest that Bell's palsy pathogenesis is associated with oxidative stress.

Keywords: Bell Palsy; Facial Nerve; Ischemia-Modified Albumin

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