Display options
Share it on

Clin Auton Res. 2020 Feb;30(1):79-83. doi: 10.1007/s10286-019-00633-9. Epub 2019 Aug 21.

ST-segment changes during tilt table testing for postural tachycardia syndrome: correlation with exercise stress test results.

Clinical autonomic research : official journal of the Clinical Autonomic Research Society

Ramya Vajapey, Erika Hutt Centeno, Erik H Van Iterson, Haitham M Ahmed, Kenneth A Mayuga

Affiliations

  1. Department of Cardiovascular Medicine, Section of Cardiac Electrophysiology and Pacing, Cleveland Clinic, 9500 Euclid Avenue, J2-2, Cleveland, OH, 44195, USA.
  2. Department of Cardiovascular Medicine, Section of Cardiac Electrophysiology and Pacing, Cleveland Clinic, 9500 Euclid Avenue, J2-2, Cleveland, OH, 44195, USA. [email protected].

PMID: 31435848 DOI: 10.1007/s10286-019-00633-9

Abstract

BACKGROUND: Prior studies have reported ECG (Electrocardiogram) changes during tilt table testing (TTT), specifically during repolarization with ST-segment and T-wave changes. The correlation with ischemic evaluation remains unclear. The purpose of this study was to analyze the prevalence of ST-segment changes during TTT in a young, otherwise healthy population of patients with postural tachycardia syndrome (POTS), and correlate them with exercise stress test results.

METHODS: Two hundred and fifty-five patients with POTS who underwent TTT and an exercise treadmill test (ETT) were analyzed.

RESULTS: Forty-five had ST-segment changes/depressions during TTT (91% female, average age 36 years). Of the 45, three had ST-segment depression during ETT; all three had negative exercise stress echocardiograms (ESEs). Two others had ST-segment depressions on ETT (but not TTT), with negative ESEs.

CONCLUSION: In a cohort of young, female, otherwise healthy patients with POTS, ST-segment changes occurred in a significant portion (18%) of patients during TTT. When evaluated with exercise stress testing, these patients had no evidence of underlying ischemia on ETT or ESE.

Keywords: Electrocardiogram; Exercise stress test; Postural tachycardia syndrome; Tilt table test

References

  1. Clin Auton Res. 2008 Jun;18(3):155-7 - PubMed
  2. Ann Noninvasive Electrocardiol. 2007 Jul;12(3):246-50 - PubMed
  3. Neurology. 1993 Jan;43(1):132-7 - PubMed
  4. J Electrocardiol. 2017 Nov - Dec;50(6):884-888 - PubMed
  5. Ann Noninvasive Electrocardiol. 2006 Jul;11(3):253-8 - PubMed
  6. Cardiovasc Ultrasound. 2017 Mar 21;15(1):7 - PubMed
  7. Circulation. 2013 Jun 11;127(23):2336-42 - PubMed
  8. Ann Noninvasive Electrocardiol. 2004 Apr;9(2):121-6 - PubMed
  9. Clin Neurophysiol. 2011 Feb;122(2):405-9 - PubMed
  10. Heart Rhythm. 2015 Jun;12(6):e41-63 - PubMed
  11. Am J Med Sci. 1999 Feb;317(2):75-7 - PubMed
  12. J Intern Med. 2019 Apr;285(4):352-366 - PubMed

Publication Types