Clin Auton Res. 2020 Feb;30(1):79-83. doi: 10.1007/s10286-019-00633-9. Epub 2019 Aug 21.
ST-segment changes during tilt table testing for postural tachycardia syndrome: correlation with exercise stress test results.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society
Ramya Vajapey, Erika Hutt Centeno, Erik H Van Iterson, Haitham M Ahmed, Kenneth A Mayuga
Affiliations
Affiliations
- Department of Cardiovascular Medicine, Section of Cardiac Electrophysiology and Pacing, Cleveland Clinic, 9500 Euclid Avenue, J2-2, Cleveland, OH, 44195, USA.
- Department of Cardiovascular Medicine, Section of Cardiac Electrophysiology and Pacing, Cleveland Clinic, 9500 Euclid Avenue, J2-2, Cleveland, OH, 44195, USA. [email protected].
PMID: 31435848
DOI: 10.1007/s10286-019-00633-9
Abstract
BACKGROUND: Prior studies have reported ECG (Electrocardiogram) changes during tilt table testing (TTT), specifically during repolarization with ST-segment and T-wave changes. The correlation with ischemic evaluation remains unclear. The purpose of this study was to analyze the prevalence of ST-segment changes during TTT in a young, otherwise healthy population of patients with postural tachycardia syndrome (POTS), and correlate them with exercise stress test results.
METHODS: Two hundred and fifty-five patients with POTS who underwent TTT and an exercise treadmill test (ETT) were analyzed.
RESULTS: Forty-five had ST-segment changes/depressions during TTT (91% female, average age 36 years). Of the 45, three had ST-segment depression during ETT; all three had negative exercise stress echocardiograms (ESEs). Two others had ST-segment depressions on ETT (but not TTT), with negative ESEs.
CONCLUSION: In a cohort of young, female, otherwise healthy patients with POTS, ST-segment changes occurred in a significant portion (18%) of patients during TTT. When evaluated with exercise stress testing, these patients had no evidence of underlying ischemia on ETT or ESE.
Keywords: Electrocardiogram; Exercise stress test; Postural tachycardia syndrome; Tilt table test
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