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J Res Med Sci. 2019 Jul 24;24:62. doi: 10.4103/jrms.JRMS_975_18. eCollection 2019.

Association between a novel G94A single nucleotide polymorphism in .

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Mohammed A Abosheasha, Faten Zahran, Sahar S Bessa, Mohammed A El-Magd, Tarek M Mohamed

Affiliations

  1. Department of Biochemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.
  2. Cellular Genetics Laboratory, Graduate School of Science, Tokyo Metropolitan University, Tokyo, 192-0397, Japan.
  3. Department of Internal Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.
  4. Department of Anatomy, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh, Egypt.
  5. Department of Chemistry, Biochemistry Division, Faculty of Science, Tanta University, Tanta, Egypt.

PMID: 31523248 PMCID: PMC6669993 DOI: 10.4103/jrms.JRMS_975_18

Abstract

BACKGROUND: Na

MATERIALS AND METHODS: A total number of 150 individuals were subclassified into healthy controls (

RESULTS: The biochemical results exhibited a significant reduction in fasting C-Peptide and activity of Na

CONCLUSION: Thus, allele A of G94A SNP (rs1060366) could be a risk allele for diabetes susceptibility among Egyptian patients.

Keywords: C-peptide; diabetes mellitus; diabetic neuropathies; polymorphism; sodium-potassium-exchanging ATPase

Conflict of interest statement

There are no conflicts of interest.

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