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Genes Environ. 2019 Sep 13;41:17. doi: 10.1186/s41021-019-0132-9. eCollection 2019.

Comprehensive framework between environment and genomic stability: the open symposium of the Japanese Environmental Mutagen Society (JEMS) in 2019.

Genes and environment : the official journal of the Japanese Environmental Mutagen Society

Katsuyoshi Horibata, Masashi Sekimoto, Kei-Ichi Sugiyama

Affiliations

  1. 1Division of Genetics and Mutagenesis, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501 Japan.
  2. 2Laboratory of Environmental Hygiene, Department of Environmental Science, School of Life and Environmental Science, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, 252-5201 Japan.

PMID: 31528240 PMCID: PMC6743095 DOI: 10.1186/s41021-019-0132-9

Abstract

The open symposium of the Japanese Environmental Mutagen Society (JEMS), under the title of "Comprehensive framework between environment and genomic stability," was held in the Main Conference Room of the Foundation for Promotion of Cancer Research, Tokyo, on June 8, 2019. To understand the relationship between genes and environmental mutagens, the symposium highlights the research activities in the fields of cancer, carcinogenesis and related diseases caused by genomic instabilities, including epigenetic and metabolomic alterations. The symposium was planned to help familiarize attendees with the current trends in research on genome safety. The organizers herein present a summary of the symposium.

Keywords: Carcinogenesis; Environmental mutagen; Epigenetic gene regulation; Genetic toxicology; Metabolomics; Mutagenesis

Conflict of interest statement

Competing interestsThe authors declare that they have no competing interests.

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