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Araújo SA, do Carmo PAS, Paulino E, et al. Pheochromocytoma-induced shock: a case report. Autops Case Rep. 2012;2(3):21-30doi: 10.4322/acr.2012.022.
Araújo, S. A., do Carmo, P. A. S., Paulino, E., Borges, I. N., & Rocha, L. O. S. (2012). Pheochromocytoma-induced shock: a case report. Autopsy & case reports, 2(3), 21-30. https://doi.org/10.4322/acr.2012.022
Araújo, Stanley de Almeida, et al. "Pheochromocytoma-induced shock: a case report." Autopsy & case reports vol. 2,3 (2012): 21-30. doi: https://doi.org/10.4322/acr.2012.022
Araújo SA, do Carmo PAS, Paulino E, Borges IN, Rocha LOS. Pheochromocytoma-induced shock: a case report. Autops Case Rep. 2012 Sep 30;2(3):21-30. doi: 10.4322/acr.2012.022. eCollection 2012. PMID: 31528576; PMCID: PMC6735568.
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Autops Case Rep. 2012 Sep 30;2(3):21-30. doi: 10.4322/acr.2012.022. eCollection 2012.

Pheochromocytoma-induced shock: a case report.

Autopsy & case reports

Stanley de Almeida Araújo, Paula Alves Santos do Carmo, Eduardo Paulino, Isabela Nascimento Borges, Luiz Otávio Savassi Rocha

Affiliations

  1. Department of Pathology and Forensic Medicine - Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte/MG - Brasil.
  2. Internal Medicine Service - Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte/MG - Brasil.
  3. Department of Internal Medicine - Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte/MG - Brasil.

PMID: 31528576 PMCID: PMC6735568 DOI: 10.4322/acr.2012.022

Abstract

Because of its rarity, together with the variability and nonspecificity of its signs and symptoms, pheochromocytoma, a tumor arising from chromaffin cells, creates an unlucky paradox: it is often missed but only rarely found. Besides the association with arterial hypertension, often in the form of paroxysmal attacks, pheochromocytoma may also be associated, in up to 40% of cases, with orthostatic hypotension which, when present, provides a clue to the diagnosis of the tumor. Far more rare (about 2% of cases) is the clinical presentation in the form of shock, a possibility that, among other attributes, justifies the epithet "the great mimic" applied to the neoplasia. The authors report the case of a 51-year-old hypertensive woman whose death was erroneously attributed to septic shock. Autopsy disclosed an unsuspected left adrenal bulky pheochromocytoma with areas of hemorrhage and extensive central necrosis, pronounced pulmonary edema, left ventricular mural thrombus, and histological evidence of acute myocardial injury.

Keywords: Autopsy; Pheochromocytoma; Shock

Conflict of interest statement

Conflict of interest: None

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