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Snovskaya MA, Namazova-Baranova LS, Kozhevnikova OV, et al. [The mode of evaluation of sensibilization of children to grain herbs under respiratory allergy.]. Klin Lab Diagn. 2017;62(5):300-304doi: 10.18821/0869-2084-2017-5-300-304.
Snovskaya, M. A., Namazova-Baranova, L. S., Kozhevnikova, O. V., Batyrova, A. S., Malyshev, V. S., Vishneva, E. A., Alekseeva, A. A., & Mityushin, I. L. (2017). [The mode of evaluation of sensibilization of children to grain herbs under respiratory allergy.]. Klinicheskaia laboratornaia diagnostika, 62(5), 300-304. https://doi.org/10.18821/0869-2084-2017-5-300-304
Snovskaya, M A, et al. "[The mode of evaluation of sensibilization of children to grain herbs under respiratory allergy.]." Klinicheskaia laboratornaia diagnostika vol. 62,5 (2017): 300-304. doi: https://doi.org/10.18821/0869-2084-2017-5-300-304
Snovskaya MA, Namazova-Baranova LS, Kozhevnikova OV, Batyrova AS, Malyshev VS, Vishneva EA, Alekseeva AA, Mityushin IL. [The mode of evaluation of sensibilization of children to grain herbs under respiratory allergy.]. Klin Lab Diagn. 2017;62(5):300-304. doi: 10.18821/0869-2084-2017-5-300-304. Russian. PMID: 31509661.
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Klin Lab Diagn. 2017;62(5):300-304. doi: 10.18821/0869-2084-2017-5-300-304.

[The mode of evaluation of sensibilization of children to grain herbs under respiratory allergy.].

Klinicheskaia laboratornaia diagnostika

[Article in Russian]
M A Snovskaya, L S Namazova-Baranova, O V Kozhevnikova, A S Batyrova, V S Malyshev, E A Vishneva, A A Alekseeva, I L Mityushin

Affiliations

  1. The scientific center of children health of Minzdrav of Russia, 119991, Moscow, Russia.
  2. The I.M. Sechenov first Moscow state medical university of Minzdrav of Russia, 119992, Moscow, Russia.
  3. The N.I. Pirogov Russian national research medical university Minzdrav of Russia, 117997, Moscow, Russia.
  4. "Fides lab", 127106, Moscow, Russia.

PMID: 31509661 DOI: 10.18821/0869-2084-2017-5-300-304

Abstract

The sensibilization of patients to allergens of grain herbs is characterized by expressed crossed allergic reactions to pollen of various representatives of the given family. The investigation of antibody response to allergens of grain herbs and also data of epidemiological studies, results of world and national studies permitted to develop and propose a new mode of diagnostic of allergy with evaluation of level of sensibilization of patient and also qualitative detection in blood serum the level of specific immunoglobulins E (IgE) to allergens of grain herbs. The parameter «concentration of IgE to allergens of cocksfoot» - IgE(g3) - is a key one for evaluating in blood serum of patients content of IgE to allergens of grain herbs matched to cocksfoot: randall, timothy, Kentucky bluegrass, field brome, meadow foxtail, French ryegrass. To calculate concentration of IgE to allergens of the mentioned grasses detection of IgE(g3) is necessary and sufficient. The elaborated prognostic table permits evaluating degree of ensibilization of patient to various grain herbs and also detecting concentration of IgE expressed in units kE per l without application of additional serological analyses. Therefore, the elaborated technique permits reducing number of «in vitro» tests and minimizing number of blood sample of patient and also speeding up receiving of information concerning sensibilization profile of patient.

Keywords: allergens of grain herbs; immunoglobulins E; regression analysis; respiratory allergy

Conflict of interest statement

The authors declare no conflict of interest.

Publication Types

Grant support