Display options
Cite
Scarano A, Lorusso F, Santos de Oliveira P, et al. Hydroxyapatite Block Produced by Sponge Replica Method: Mechanical, Clinical and Histologic Observations. Materials (Basel). 2019;12(19)doi: 10.3390/ma12193079.
Scarano, A., Lorusso, F., Santos de Oliveira, P., Kunjalukkal Padmanabhan, S., & Licciulli, A. (2019). Hydroxyapatite Block Produced by Sponge Replica Method: Mechanical, Clinical and Histologic Observations. Materials (Basel, Switzerland), 12(19), . https://doi.org/10.3390/ma12193079
Scarano, Antonio, et al. "Hydroxyapatite Block Produced by Sponge Replica Method: Mechanical, Clinical and Histologic Observations." Materials (Basel, Switzerland) vol. 12,19 (2019). doi: https://doi.org/10.3390/ma12193079
Scarano A, Lorusso F, Santos de Oliveira P, Kunjalukkal Padmanabhan S, Licciulli A. Hydroxyapatite Block Produced by Sponge Replica Method: Mechanical, Clinical and Histologic Observations. Materials (Basel). 2019 Sep 21;12(19). doi: 10.3390/ma12193079. PMID: 31546617; PMCID: PMC6804165.
Copy Download .nbib Format: NLM
Share it on

Materials (Basel). 2019 Sep 21;12(19). doi: 10.3390/ma12193079.

Hydroxyapatite Block Produced by Sponge Replica Method: Mechanical, Clinical and Histologic Observations.

Materials (Basel, Switzerland)

Antonio Scarano, Felice Lorusso, Pablo Santos de Oliveira, Sanosh Kunjalukkal Padmanabhan, Antonio Licciulli

Affiliations

  1. Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy. [email protected].
  2. Department of Oral Implantology, Dental Research Division, College Ingà, UNINGÁ, Cachoeiro de Itapemirim 29312, Brazil. [email protected].
  3. Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy. [email protected].
  4. Department of Oral Implantology, Dental Research Division, College Ingà, UNINGÁ, Cachoeiro de Itapemirim 29312, Brazil. [email protected].
  5. Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy. [email protected].
  6. Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy. [email protected].

PMID: 31546617 PMCID: PMC6804165 DOI: 10.3390/ma12193079

Abstract

PURPOSE: The grafting procedure for the anthropic ridges of jaws represents a surgical technique for increasing the bone volume to permit the placement of dental implants for oral rehabilitations. The aim of this study was to evaluate a hydroxyapatite (HA) porous scaffold produced via a sponge replica method for the treatment of maxillary bone defects in a human model.

METHODS: A total of thirteen patients were treated for sinus lifting in the posterior maxilla for a total of 16 defects treated with cylindrical HA Block. The experimental sites were evaluated by a 3D Cone Beam Computer Tomography scan (CBCT), and the histological analysis was performed after 3 months of healing.

RESULTS: After the 3 months healing period, the histological outcome of the investigation showed a high level of biological osteoconduction of the HA. Microscopical evidence of new bone formation was also observed in the central portion of the graft block. The samples were composed of different tissues: 39 ± 1% new bone, 42 ± 3% marrow space, 17 ± 3% residual HA Block and 4.02 ± 2% osteoid tissue were present. The new bone formation in the block was 8 ± 3%

Keywords: cone beam computed tomography; histology; hydroxyapatite; scaffold; sponge replica

References

  1. J Biochem. 1997 Feb;121(2):317-24 - PubMed
  2. Int J Pharm. 2017 May 25;523(2):534-544 - PubMed
  3. J Periodontol. 2008 May;79(5):929-33 - PubMed
  4. J Dent. 2018 Dec;79:102-106 - PubMed
  5. Biomaterials. 2005 Sep;26(27):5474-91 - PubMed
  6. Int Orthop. 2019 Mar;43(3):539-551 - PubMed
  7. J Funct Biomater. 2018 Nov 08;9(4):null - PubMed
  8. J Bone Miner Res. 2013 Jan;28(1):2-17 - PubMed
  9. Materials (Basel). 2018 Aug 17;11(8):null - PubMed
  10. Int J Oral Maxillofac Implants. 2007 Nov-Dec;22(6):980-6 - PubMed
  11. J Tissue Eng. 2016 May 17;7:2041731416648810 - PubMed
  12. J Oral Surg. 1980 Aug;38(8):613-6 - PubMed
  13. Front Physiol. 2017 Aug 03;8:565 - PubMed
  14. Curr Pharm Biotechnol. 2017;18(1):33-44 - PubMed
  15. Clin Oral Implants Res. 2018 May;29(5):465-479 - PubMed
  16. Biomaterials. 1996 Mar;17(5):523-8 - PubMed
  17. Int J Periodontics Restorative Dent. 2007 Dec;27(6):596-601 - PubMed
  18. Implant Dent. 2003;12(4):318-24 - PubMed
  19. Br J Oral Maxillofac Surg. 2005 Feb;43(1):51-6 - PubMed
  20. Int J Environ Res Public Health. 2018 Jun 16;15(6): - PubMed
  21. Clin Oral Implants Res. 2003 Aug;14(4):500-8 - PubMed
  22. J Oral Implantol. 2006;32(3):122-31 - PubMed
  23. Biomaterials. 2019 Jul;209:152-162 - PubMed
  24. Clin Implant Dent Relat Res. 2004;6(3):165-73 - PubMed
  25. Dent Clin North Am. 1986 Apr;30(2):207-29 - PubMed
  26. Pharmaceutics. 2018 Aug 08;10(3):null - PubMed
  27. J Periodontol. 2011 Mar;82(3):403-12 - PubMed
  28. J Oral Maxillofac Surg. 1987 Sep;45(9):771-8 - PubMed
  29. Oral Maxillofac Surg. 2011 Dec;15(4):239-43 - PubMed
  30. J Oral Implantol. 2004;30(6):376-83 - PubMed
  31. Curr Pharm Biotechnol. 2017;18(1):19-32 - PubMed
  32. Biomed Res Int. 2016;2016:4086870 - PubMed
  33. Biomaterials. 1997 Apr;18(7):577-9 - PubMed
  34. Spine (Phila Pa 1976). 2005 Aug 1;30(15):1756-61 - PubMed
  35. J Craniofac Surg. 2013 May;24(3):856-9 - PubMed
  36. J Funct Biomater. 2015 Dec 21;6(4):1099-140 - PubMed
  37. Int J Oral Maxillofac Implants. 2002 Sep-Oct;17(5):635-43 - PubMed
  38. Int Orthop. 2012 Aug;36(8):1583-8 - PubMed
  39. Int J Periodontics Restorative Dent. 1998 Dec;18(6):528-43 - PubMed

Publication Types