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Front Neurol. 2019 Sep 23;10:984. doi: 10.3389/fneur.2019.00984. eCollection 2019.

Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases.

Frontiers in neurology

Agnès Aghetti, Damien Sène, Marc Polivka, Natalia Shor, Sarah Lechtman, Hugues Chabriat, Eric Jouvent, Stéphanie Guey

Affiliations

  1. APHP, Lariboisière Hospital, Department of Neurology and DHU NeuroVasc Sorbonne Paris Cité, Paris, France.
  2. INSERM UMR-S 1141, Paris, France.
  3. Department of Internal Medicine, Lariboisière Hospital, AP-HP, Paris, France.
  4. Univ Paris Diderot, Sorbonne Paris Cité, Paris, France.
  5. Department of Pathology, Lariboisière Hospital, AP-HP, Paris, France.
  6. Department of Radiology, La Pitié-Salpétrière Hospital, AP-HP, Paris, France.

PMID: 31608002 PMCID: PMC6768005 DOI: 10.3389/fneur.2019.00984

Abstract

Cerebral amyloid angiopathy related inflammation (CAA-RI) is a rare form of CAA characterized by subacute encephalitic symptoms (cognitive decline, seizures, focal deficits) associated with extensive and confluent white matter lesions co-localizing with lobar microbleeds on brain MRI. We report two cases of unusual CAA-RI mimicking meningoencephalitis but without typical brain lesions on FLAIR and T2

Copyright © 2019 Aghetti, Sène, Polivka, Shor, Lechtman, Chabriat, Jouvent and Guey.

Keywords: cerebral amyloid angiopathy (CAA); cerebral amyloid angiopathy-related inflammation (CAA-RI); meningeal inflammation; subarachnoid hemorrhage; xanthochromia

References

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