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Aggarwal A, Jaswal N, Jain R, et al. Amoxicillin-clavulanate-induced Granulomatous Hepatitis: Case Report and Review of the Literature. J Clin Transl Hepatol. 2019;7(3):280-283doi: 10.14218/JCTH.2019.00027.
Aggarwal, A., Jaswal, N., Jain, R., & Elsiesy, H. (2019). Amoxicillin-clavulanate-induced Granulomatous Hepatitis: Case Report and Review of the Literature. Journal of clinical and translational hepatology, 7(3), 280-283. https://doi.org/10.14218/JCTH.2019.00027
Aggarwal, Avin, et al. "Amoxicillin-clavulanate-induced Granulomatous Hepatitis: Case Report and Review of the Literature." Journal of clinical and translational hepatology vol. 7,3 (2019): 280-283. doi: https://doi.org/10.14218/JCTH.2019.00027
Aggarwal A, Jaswal N, Jain R, Elsiesy H. Amoxicillin-clavulanate-induced Granulomatous Hepatitis: Case Report and Review of the Literature. J Clin Transl Hepatol. 2019 Sep 28;7(3):280-283. doi: 10.14218/JCTH.2019.00027. Epub 2019 Jul 26. PMID: 31608221; PMCID: PMC6783680.
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J Clin Transl Hepatol. 2019 Sep 28;7(3):280-283. doi: 10.14218/JCTH.2019.00027. Epub 2019 Jul 26.

Amoxicillin-clavulanate-induced Granulomatous Hepatitis: Case Report and Review of the Literature.

Journal of clinical and translational hepatology

Avin Aggarwal, Neha Jaswal, Richa Jain, Hussien Elsiesy

Affiliations

  1. Department of Medicine, University of Arizona, Tucson, AZ, USA.
  2. Department of Pathology, University of Arizona, Tucson, AZ, USA.
  3. Liver consultants of Texas, Baylor All Saints Medical Center, Fort Worth, TX, USA.

PMID: 31608221 PMCID: PMC6783680 DOI: 10.14218/JCTH.2019.00027

Abstract

Amoxicillin-clavulanate (AC) is a common cause of drug-induced liver injury, either cholestatic or mixed with hepatitis pattern. Rarely, AC causes granulomatous hepatitis. We report a new case of AC-induced granulomatous hepatitis documented by liver biopsy, with complete resolution of any histological sequelae on a follow-up liver biopsy after AC was withdrawn.

© 2019 Authors.

Keywords: Amoxicillin; Clavulanate; Drug-induced liver injury; Granulomatous hepatitis; Liver biopsy

Conflict of interest statement

The authors have no conflict of interests related to this publication.

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