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Karamolahi S, Yazdi RS, Zangeneh M, et al. Impact of hepatitis B virus and hepatitis C virus infection on sperm parameters of infertile men. Int J Reprod Biomed. 2019;17(8):551-556doi: 10.18502/ijrm.v17i8.4820.
Karamolahi, S., Yazdi, R. S., Zangeneh, M., Makiani, M. J., Farhoodi, B., & Gilani, M. A. S. (2019). Impact of hepatitis B virus and hepatitis C virus infection on sperm parameters of infertile men. International journal of reproductive biomedicine, 17(8), 551-556. https://doi.org/10.18502/ijrm.v17i8.4820
Karamolahi, Sana, et al. "Impact of hepatitis B virus and hepatitis C virus infection on sperm parameters of infertile men." International journal of reproductive biomedicine vol. 17,8 (2019): 551-556. doi: https://doi.org/10.18502/ijrm.v17i8.4820
Karamolahi S, Yazdi RS, Zangeneh M, Makiani MJ, Farhoodi B, Gilani MAS. Impact of hepatitis B virus and hepatitis C virus infection on sperm parameters of infertile men. Int J Reprod Biomed. 2019 Sep 03;17(8):551-556. doi: 10.18502/ijrm.v17i8.4820. eCollection 2019 Aug. PMID: 31583372; PMCID: PMC6745080.
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Int J Reprod Biomed. 2019 Sep 03;17(8):551-556. doi: 10.18502/ijrm.v17i8.4820. eCollection 2019 Aug.

Impact of hepatitis B virus and hepatitis C virus infection on sperm parameters of infertile men.

International journal of reproductive biomedicine

Sana Karamolahi, Reza Salman Yazdi, Mehrangiz Zangeneh, Mahin Jamshidi Makiani, Behnam Farhoodi, Mohammad Ali Sedighi Gilani

Affiliations

  1. Tehran Medical Sciences, Branch Islamic Azad University Tehran Iran.
  2. Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR Tehran Iran.
  3. Department of Infectious Diseases, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University Tehran Iran.
  4. Department of Infectious Diseases, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR Tehran Iran.
  5. Antimicrobial Resistance Research Center, Institute of Immunology & Infectious Diseases, Iran University of Medical Sciences Tehran Iran.

PMID: 31583372 PMCID: PMC6745080 DOI: 10.18502/ijrm.v17i8.4820

Abstract

BACKGROUND: Viral hepatitis is one of the health problems which have the effects on the health issues. It seems that hepatitis B virus (HBV) and hepatitis C virus (HCV) infection have negative impacts on the semen quality and male infertility rate.

OBJECTIVE: In this study, we aimed to evaluate the effects of HBV and HCV on sperm quality among Iranian infertile men referred to Royan Institute Reproductive Biomedicine Research Center between 2003 and 2014.

MATERIALS AND METHODS: This retrospective case-control study included 112 HBV positive infertile men and 47 HCV positive infertile men as case group and 112 HBV negative and HCV negative matched infertile men as a control group. All semen analysis and viral parameters assessment was performed in the central laboratory with the same method and instruments.

RESULTS: Sperm count among infertile men with HBV and HCV infection was significantly lower than control group [the mean of the total sperm count 100.95░±░118.59, 118.22░±░141.18, 166.27░±░151.25 (p░<░0.001)]. Sperm motility was significantly decreased in HBV and HCV positive men in comparison to the control group [30.97░±░25.88, 31.09░±░28.72, 40.87░±░23.37, respectively (p░<░0.007)]. The percentage of normal sperm morphology was significantly higher in control group in comparison to HBV and HCV infected group [the mean of the normal semen morphology 3.23░±░3.27, 3.70░±░3.83, 4.51░±░3.15 p░<░0.015]. Although there is a significant decline in liquefaction time in the case group but the viscosity, semen volume, and PH of semen samples were similar in the both case and control groups.

CONCLUSION: Our results suggest that HBV and HCV infection are associated with poor sperm quality.

Copyright © 2019 Sana karamolahi et al.

Keywords: Hepatitis B virus; Hepatitis C virus; Infertility; Male; Sperm

Conflict of interest statement

The authors declare no financial interests.

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