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Infect Chemother. 2019 Sep;51(3):305-309. doi: 10.3947/ic.2019.51.3.305.

Modified Measles in an Anti-Measles Immunoglobulin G-negative Healthcare Worker who had Received Two Doses of Measles-Containing Vaccine.

Infection & chemotherapy

Jung Wan Park, Shi Nae Yu, Eunkyeong Park, Yunseo Lee, Sun Mi Park, Min Hyok Jeon

Affiliations

  1. Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Korea.
  2. Office for Infection Control, Soonchunhyang University Cheonan Hospital, Korea.
  3. Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Korea. [email protected].

PMID: 31583864 PMCID: PMC6779578 DOI: 10.3947/ic.2019.51.3.305

Abstract

To date, documentation of two doses of measles-containing vaccine (MCV) has been accepted as confirmation of measles immunity among healthcare workers (HCWs). However, we encountered measles in an HCW who had received two doses of MCV. A patient with measles was admitted to our hospital. Among 62 exposed HCWs, one nurse who had previously received two doses of MCV was shown to be negative for anti-measles immunoglobulin G (IgG), and was confirmed to have measles 14 days after exposure. Based on this experience, we suggest that all HCWs should be tested for anti-measles IgG to confirm their immunity to measles.

Copyright © 2019 by The Korean Society of Infectious Diseases and Korean Society for Antimicrobial Therapy.

Keywords: Measles; Measles vaccine; Measles-mumps-rubella vaccine; Patient-to-professional transmission

Conflict of interest statement

No conflicts of interest.

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