Display options
Cite
Esposito D, Overall J, Grace MH, et al. Alaskan Berry Extracts Promote Dermal Wound Repair Through Modulation of Bioenergetics and Integrin Signaling. Front Pharmacol. 2019;10:1058doi: 10.3389/fphar.2019.01058.
Esposito, D., Overall, J., Grace, M. H., Komarnytsky, S., & Lila, M. A. (2019). Alaskan Berry Extracts Promote Dermal Wound Repair Through Modulation of Bioenergetics and Integrin Signaling. Frontiers in pharmacology, 101058. https://doi.org/10.3389/fphar.2019.01058
Esposito, Debora, et al. "Alaskan Berry Extracts Promote Dermal Wound Repair Through Modulation of Bioenergetics and Integrin Signaling." Frontiers in pharmacology vol. 10 (2019): 1058. doi: https://doi.org/10.3389/fphar.2019.01058
Esposito D, Overall J, Grace MH, Komarnytsky S, Lila MA. Alaskan Berry Extracts Promote Dermal Wound Repair Through Modulation of Bioenergetics and Integrin Signaling. Front Pharmacol. 2019 Sep 27;10:1058. doi: 10.3389/fphar.2019.01058. eCollection 2019. PMID: 31611784; PMCID: PMC6776586.
Copy Download .nbib Format: NLM
Share it on

Front Pharmacol. 2019 Sep 27;10:1058. doi: 10.3389/fphar.2019.01058. eCollection 2019.

Alaskan Berry Extracts Promote Dermal Wound Repair Through Modulation of Bioenergetics and Integrin Signaling.

Frontiers in pharmacology

Debora Esposito, John Overall, Mary H Grace, Slavko Komarnytsky, Mary Ann Lila

Affiliations

  1. Food Bioprocessing and Nutrition Sciences Department, Plants for Human Health Institute, North Carolina State University, Kannapolis, NC, United States.
  2. Department of Animal Science, North Carolina State University, Raleigh, NC, United States.
  3. Department of Food, Bioprocessing, and Nutrition Sciences, North Carolina State University, Raleigh, NC, United States.

PMID: 31611784 PMCID: PMC6776586 DOI: 10.3389/fphar.2019.01058

Abstract

Various wild berry species endemic to Alaska and the circumpolar North that exhibit unique medicinal properties have long been appreciated by indigenous Arctic communities. Traditional use of Alaskan berry preparations in the treatment of skin wounds is recorded but has not been scientifically evaluated. Alaskan wild berries feature diverse phytochemical compositions that contain a variety of bioactive polyphenols exhibiting anti-inflammatory, antioxidant, and antimicrobial properties, making them ideal for wound healing interventions and natural anti-aging cosmeceutical formulations. Given increasing interest in identifying biologically active plant constituents for wound care and cosmeceutical applications, the objective of this study was to screen several wild berry species endemic to Alaska and the circumpolar Artic for wound healing and in the crude, polyphenol-enriched, and further fractionated extracts of:

Copyright © 2019 Esposito, Overall, Grace, Komarnytsky and Lila.

Keywords: Alaskan berries; epicatechins; integrins; proanthocyanidins; skin regeneration; wound healing

References

  1. Nutrition. 2014 Feb;30(2):134-44 - PubMed
  2. Postepy Dermatol Alergol. 2013 Jun;30(3):170-7 - PubMed
  3. Arch Oral Biol. 2011 Aug;56(8):812-22 - PubMed
  4. Sci Rep. 2018 Jul 5;8(1):10216 - PubMed
  5. Am J Pathol. 2004 Jul;165(1):299-307 - PubMed
  6. J Agric Food Chem. 2008 Feb 13;56(3):627-9 - PubMed
  7. Molecules. 2017 Dec 22;23(1):null - PubMed
  8. Science. 2017 Jun 9;356(6342):1026-1030 - PubMed
  9. J Agric Food Chem. 2014 Jul 23;62(29):7022-8 - PubMed
  10. J Cell Sci. 2009 Jan 15;122(Pt 2):199-206 - PubMed
  11. Ecohealth. 2011 Jun;8(2):199-209 - PubMed
  12. Physiology (Bethesda). 2013 Nov;28(6):380-90 - PubMed
  13. Environ Health Perspect. 2017 Aug 29;125(8):085006 - PubMed
  14. J Pharmacol Exp Ther. 2003 Jul;306(1):29-34 - PubMed
  15. Nat Rev Mol Cell Biol. 2014 Dec;15(12):802-12 - PubMed
  16. J Sci Food Agric. 2010 Jul;90(9):1473-8 - PubMed
  17. J Agric Food Chem. 2013 May 22;61(20):4806-15 - PubMed
  18. J Agric Food Chem. 2010 Apr 14;58(7):3884-900 - PubMed
  19. Sci Signal. 2017 Sep 05;10(495):null - PubMed
  20. Crit Rev Food Sci Nutr. 2018 May 24;58(8):1310-1329 - PubMed
  21. Food Chem Toxicol. 2009 Nov;47(11):2806-12 - PubMed
  22. Adv Drug Deliv Rev. 2018 Apr;129:37-53 - PubMed
  23. J Ethnopharmacol. 2007 Aug 15;113(1):149-55 - PubMed
  24. Cell Mol Life Sci. 2016 Oct;73(20):3861-85 - PubMed
  25. Matrix Biol. 2018 Oct;71-72:205-224 - PubMed
  26. Adv Skin Wound Care. 2006 Jul-Aug;19(6):324-7 - PubMed
  27. Plant Foods Hum Nutr. 2010 Sep;65(3):299-308 - PubMed
  28. J Nutr. 2004 Dec;134(12 Suppl):3479S-3485S - PubMed
  29. PLoS One. 2014 Mar 11;9(3):e91574 - PubMed
  30. Int J Mol Sci. 2016 Feb 18;17(2):160 - PubMed
  31. Int J Mol Sci. 2016 Aug 04;17(8): - PubMed
  32. Front Plant Sci. 2016 May 18;7:655 - PubMed
  33. Phytomedicine. 2009 May;16(5):406-15 - PubMed
  34. Methods. 2001 Dec;25(4):402-8 - PubMed
  35. J Agric Food Chem. 2014 May 7;62(18):4007-17 - PubMed
  36. Am J Pathol. 2004 Jun;164(6):1935-47 - PubMed
  37. Exp Cell Res. 2015 Jun 10;334(2):337-49 - PubMed
  38. J Chromatogr A. 2017 Apr 28;1495:46-56 - PubMed
  39. Br J Dermatol. 2017 Nov;177(5):1337-1348 - PubMed
  40. Wound Repair Regen. 2015 Mar-Apr;23(2):171-83 - PubMed
  41. J Nat Prod. 2010 Dec 27;73(12):2035-41 - PubMed
  42. Front Aging Neurosci. 2016 Jul 18;8:173 - PubMed
  43. Mol Biol Cell. 2017 Jul 7;28(14):1833-1846 - PubMed
  44. J Dent Res. 2011 Dec;90(12):1367-76 - PubMed
  45. Int Wound J. 2017 Jun;14(3):450-459 - PubMed
  46. Geroscience. 2018 Apr;40(2):151-162 - PubMed

Publication Types