J Pharm Bioallied Sci. 2019 Jul-Sep;11(3):268-275. doi: 10.4103/jpbs.JPBS_134_19.
[No title available]
Journal of pharmacy & bioallied sciences
Cyrus Jalili, Shiva Roshankhah, Mohammad Reza Salahshoor
Affiliations
Affiliations
- Department of Anatomical Sciences, Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
- Department of Anatomy, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
PMID: 31555034
PMCID: PMC6662036 DOI: 10.4103/jpbs.JPBS_134_19
Abstract
BACKGROUND: Alcohol consumption is capable of producing free radicals and inducing disturbance in body antioxidant.
MATERIALS AND METHODS: Forty-eight Wistar rats were divided randomly into eight groups (
RESULTS: Ethanol administration increased significantly Bowman's space, qualitative histopathology indices, kidney malondialdehyde (MDA) level, blood urea nitrogen (BUN), creatinine, and nitrite oxide levels and decreased significantly total antioxidant capacity (TAC) level and diameter and number of renal corpuscles compared to that in the control normal group (
CONCLUSION: It seems that
Keywords: Ethanol; Falcaria vulgaris; lipid peroxidation; oxidative stress; renal damage
Conflict of interest statement
There are no conflicts of interest.
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