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Zhang Y, Xu SY, Liu MN, et al. Comparative Studies on Chemical Contents and Effect in Kidney-Yang Deficiency Rats of Salt-Processed Product and Wine-Processed Product of Cuscutae Semen. Evid Based Complement Alternat Med. 2019;2019:2049497doi: 10.1155/2019/2049497.
Zhang, Y., Xu, S. Y., Liu, M. N., Jia, T. Y., Qu, W. J., Han, T., Jia, Z., Xu, X. F., & Li, X. R. (2019). Comparative Studies on Chemical Contents and Effect in Kidney-Yang Deficiency Rats of Salt-Processed Product and Wine-Processed Product of Cuscutae Semen. Evidence-based complementary and alternative medicine : eCAM, 20192049497. https://doi.org/10.1155/2019/2049497
Zhang, Ying, et al. "Comparative Studies on Chemical Contents and Effect in Kidney-Yang Deficiency Rats of Salt-Processed Product and Wine-Processed Product of Cuscutae Semen." Evidence-based complementary and alternative medicine : eCAM vol. 2019 (2019): 2049497. doi: https://doi.org/10.1155/2019/2049497
Zhang Y, Xu SY, Liu MN, Jia TY, Qu WJ, Han T, Jia Z, Xu XF, Li XR. Comparative Studies on Chemical Contents and Effect in Kidney-Yang Deficiency Rats of Salt-Processed Product and Wine-Processed Product of Cuscutae Semen. Evid Based Complement Alternat Med. 2019 Aug 29;2019:2049497. doi: 10.1155/2019/2049497. eCollection 2019. PMID: 31558908; PMCID: PMC6735186.
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Evid Based Complement Alternat Med. 2019 Aug 29;2019:2049497. doi: 10.1155/2019/2049497. eCollection 2019.

Comparative Studies on Chemical Contents and Effect in Kidney-Yang Deficiency Rats of Salt-Processed Product and Wine-Processed Product of Cuscutae Semen.

Evidence-based complementary and alternative medicine : eCAM

Ying Zhang, Shu-Ya Xu, Meng-Nan Liu, Tian-Ying Jia, Wen-Jia Qu, Ting Han, Zhe Jia, Xin-Fang Xu, Xiang-Ri Li

Affiliations

  1. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Higher Education Garden, Liangxiang, Fangshan District, Beijing 102488, China.
  2. College of Pharmacy Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.

PMID: 31558908 PMCID: PMC6735186 DOI: 10.1155/2019/2049497

Abstract

Cuscutae Semen mainly includes salt-processed product (SPP) and wine-processed product (WPP), which are most commonly used in traditional Chinese medicine. However, the differences between SPP and WPP have not been reported. In this paper, comparative studies between SPP and WPP on chemical contents and effect in kidney-yang deficiency rats have been investigated. UPLC-MS/MS was used to study the differences in chemical components. Kidney-yang deficiency was induced by hydrocortisone in rats. Rats were orally administrated with different doses of Jinkui Shenqi Pills, SPP, and WPP for 28 days. The average organ coefficients, renal function indexes, sex hormone levels, and testicular morphology were detected. As a result, the contents of flavonoids and chlorogenic acids were higher in SPP than in WPP, which may be caused by different processing methods. The improvement on reproduction of SPP was reflected in organ coefficients, renal function indexes, and biochemical properties of seminal plasma; furthermore, WPP was in sex hormone levels and morphology of testis. As a conclusion, these results indicated that both SPP and WPP can improve the reproductive function of kidney-yang deficiency rats with different mechanisms, which may be due to the differences in chemical contents between WPP and SPP as well as different processing methods. It is the first time that the differences between SPP and WPP have been studied in reproductive function in rats with kidney-yang deficiency.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

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