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S Afr J Psychiatr. 2019 Sep 30;25:1111. doi: 10.4102/sajpsychiatry.v25i0.1111. eCollection 2019.

Psychoactive substance use among outpatients with severe mental illness: A comparative study.

The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa

Oladipo A Sowunmi, Gbolagade Amoo, Peter O Onifade, Adegboyega Ogunwale, Emmanuel Babalola

Affiliations

  1. Neuropsychiatric Hospital, Aro, Abeokuta, Nigeria.

PMID: 31616577 PMCID: PMC6779966 DOI: 10.4102/sajpsychiatry.v25i0.1111

Abstract

BACKGROUND: Despite several studies on the prevalence and pattern of substance use in Nigeria, there is little information on substance use in patients diagnosed with serious mental illness (SMI) such as schizophrenia and bipolar affective disorder (BD).

AIM: The aim of the study was to compare the pattern of psychoactive substance use among outpatients with BD and schizophrenia.

SETTING: The study was conducted in a neuropsychiatric hospital in Nigeria.

METHODS: Seventy five consecutive patients with a MINI-PLUS diagnosis of BD were compared with an equal number of patients obtained by systematic random sampling with a MINI-PLUS diagnosis of schizophrenia.

RESULTS: The respondents with schizophrenia were aged 18-59 years (37.2 ± 9.99) and were predominantly young adult (49, 65.3%), men (46, 61.3%), who were never married (38, 50.7%). Overall, lifetime drug use prevalence was 52%, while for current use, overall prevalence was 21.3%. Participants with BD were aged 18-63 years (36.7 ± 10.29) and were predominantly young adult (53, 70.7%), women (44, 58.7%), who were married (32, 42.7%), with tertiary education (31, 41.3%). Overall, lifetime drug use prevalence was 46.7%, while current overall prevalence was 17.3%. These rates (lifetime and current) for both diagnostic groups are higher than what was reported by the World Health Organization in the global status report of 2014 (0% - 16%). The statistically significant difference between the two diagnostic groups was related to their sociodemographic and clinical variables and psychoactive substance use.

CONCLUSION: Psychoactive substance use remains a burden in the care of patients diagnosed with schizophrenia and BD. Future policies should incorporate routine screening for substance use at the outpatient department with a view to stemming the tide of this menace.

© 2019. The Authors.

Keywords: bipolar disorder; drug use; psychoactive substance use; schizophrenia; severe mental disorder

Conflict of interest statement

The authors have declared that no competing interests exist.

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