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Ryan KR, Jones MB, Allen KY, et al. Neurodevelopmental Outcomes Among Children With Congenital Heart Disease: At-Risk Populations and Modifiable Risk Factors. World J Pediatr Congenit Heart Surg. 2019;10(6):750-758doi: 10.1177/2150135119878702.
Ryan, K. R., Jones, M. B., Allen, K. Y., Marino, B. S., Casey, F., Wernovsky, G., & Lisanti, A. J. (2019). Neurodevelopmental Outcomes Among Children With Congenital Heart Disease: At-Risk Populations and Modifiable Risk Factors. World journal for pediatric & congenital heart surgery, 10(6), 750-758. https://doi.org/10.1177/2150135119878702
Ryan, Kathleen R, et al. "Neurodevelopmental Outcomes Among Children With Congenital Heart Disease: At-Risk Populations and Modifiable Risk Factors." World journal for pediatric & congenital heart surgery vol. 10,6 (2019): 750-758. doi: https://doi.org/10.1177/2150135119878702
Ryan KR, Jones MB, Allen KY, Marino BS, Casey F, Wernovsky G, Lisanti AJ. Neurodevelopmental Outcomes Among Children With Congenital Heart Disease: At-Risk Populations and Modifiable Risk Factors. World J Pediatr Congenit Heart Surg. 2019 Nov;10(6):750-758. doi: 10.1177/2150135119878702. Epub 2019 Oct 28. PMID: 31658880.
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World J Pediatr Congenit Heart Surg. 2019 Nov;10(6):750-758. doi: 10.1177/2150135119878702. Epub 2019 Oct 28.

Neurodevelopmental Outcomes Among Children With Congenital Heart Disease: At-Risk Populations and Modifiable Risk Factors.

World journal for pediatric & congenital heart surgery

Kathleen R Ryan, Melissa B Jones, Kiona Y Allen, Bradley S Marino, Frank Casey, Gil Wernovsky, Amy Jo Lisanti

Affiliations

  1. Division of Cardiology, Lucile Packard Children's Hospital Stanford, Palo Alto, CA, USA.
  2. Division of Cardiac Critical Care, Children's National Health System, Washington, DC, USA.
  3. Division of Pediatric Cardiology, Children's National Health System, Washington, DC, USA.
  4. Division of Cardiology, Ann and Robert H. Lurie Children's Hospital of Chicago, IL, USA.
  5. Division of Critical Care Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, IL, USA.
  6. Department of Cardiology, Belfast Health and Social Care Trust, Belfast, Ireland.
  7. Department of Cardiac Nursing and the Center for Pediatric Nursing Research and Evidence-based Practice, Children's Hospital of Philadelphia, PA, USA.

PMID: 31658880 DOI: 10.1177/2150135119878702

Abstract

As survivable outcomes among patients with complex congenital heart disease (cCHD) have continued to improve over the last several decades, more attention is being dedicated to interventions that impact not just survival but quality of life among patients with cCHD. In particular, patients with cCHD are at risk for impaired neurodevelopmental outcomes. In this review summarizing select presentations given at the 14th Annual Pediatric Cardiac Intensive Care Society's Annual Meeting in 2019, we discuss the neurodevelopmental phenotype of patients with cCHD, patients at greatest risk of impaired development, and three specific modifiable risk factors impacting development.

Keywords: congenital heart disease; congenital heart surgery; developmental phenotype; long term outcomes; neurodevelopment

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