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Selliez L, Maillard J, Cherville B, et al. High-resolution mass spectrometry for future space missions: Comparative analysis of complex organic matter with LAb-CosmOrbitrap and laser desorption/ionization Fourier transform ion cyclotron resonance. Rapid Commun Mass Spectrom. 2020;34(10):e8645doi: 10.1002/rcm.8645.
Selliez, L., Maillard, J., Cherville, B., Gautier, T., Thirkell, L., Gaubicher, B., Schmitz-Afonso, I., Afonso, C., Briois, C., & Carrasco, N. (2020). High-resolution mass spectrometry for future space missions: Comparative analysis of complex organic matter with LAb-CosmOrbitrap and laser desorption/ionization Fourier transform ion cyclotron resonance. Rapid communications in mass spectrometry : RCM, 34(10), e8645. https://doi.org/10.1002/rcm.8645
Selliez, Laura, et al. "High-resolution mass spectrometry for future space missions: Comparative analysis of complex organic matter with LAb-CosmOrbitrap and laser desorption/ionization Fourier transform ion cyclotron resonance." Rapid communications in mass spectrometry : RCM vol. 34,10 (2020): e8645. doi: https://doi.org/10.1002/rcm.8645
Selliez L, Maillard J, Cherville B, Gautier T, Thirkell L, Gaubicher B, Schmitz-Afonso I, Afonso C, Briois C, Carrasco N. High-resolution mass spectrometry for future space missions: Comparative analysis of complex organic matter with LAb-CosmOrbitrap and laser desorption/ionization Fourier transform ion cyclotron resonance. Rapid Commun Mass Spectrom. 2020 May 30;34(10):e8645. doi: 10.1002/rcm.8645. PMID: 31671213.
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Rapid Commun Mass Spectrom. 2020 May 30;34(10):e8645. doi: 10.1002/rcm.8645.

High-resolution mass spectrometry for future space missions: Comparative analysis of complex organic matter with LAb-CosmOrbitrap and laser desorption/ionization Fourier transform ion cyclotron resonance.

Rapid communications in mass spectrometry : RCM

Laura Selliez, Julien Maillard, Barnabe Cherville, Thomas Gautier, Laurent Thirkell, Bertrand Gaubicher, Isabelle Schmitz-Afonso, Carlos Afonso, Christelle Briois, Nathalie Carrasco

Affiliations

  1. Laboratoire de physique et Chimie de l'Environnement et de l'Espace (LPC2E), Orléans, France.
  2. Laboratoire Atmosphères, Milieux et Observations Spatiales (LATMOS), Guyancourt, France.
  3. Université de Rouen, Laboratoire COBRA UMR 6014 & FR 3038, IRCOF, 1 rue Tesnière, 76821, Mont-Saint-Aignan Cedex, France.

PMID: 31671213 DOI: 10.1002/rcm.8645

Abstract

RATIONALE: Mass spectrometers are regularly boarded on spacecraft for the exploration of the Solar System. A better understanding of the origin, distribution and evolution of organic matter and its relationships with inorganic matter in different extra-terrestrial environments requires the development of innovative space tools, described as Ultra-High-Resolution Mass Spectrometry (UHRMS) instruments.

METHODS: Analyses of a complex organic material simulating extraterrestrial matter (Titan's tholins) are performed with a homemade space-designed Orbitrap™ equipped with a laser ablation ionization source at 266 nm: the LAb-CosmOrbitrap. Mass spectra are obtained using only one laser shot and transient duration of 838 ms. A comparison is made on the same sample with a laboratory benchmark mass spectrometer: a Fourier Transform Ion Cyclotron Resonance equipped with a laser desorption ionization source at 355 nm (LDI-FTICR) allowing accumulation of 20,000 laser shots.

RESULTS: Mass spectra and attributions of molecular formulae based on the peaks detected by both techniques show significant similarities. Detection and identification of the same species are validated. The formation of clusters ions with the LAb-CosmOrbitrap is also presented. This specific feature brings informative and unusual indirect detections about the chemical compounds constituting Titan's tholins. In particular, the detection of HCN confirms previous results obtained with laboratory Electrospray Ionization (ESI)-UHRMS studies about the understanding of polymeric patterns for the formation of tholins.

CONCLUSIONS: The capabilities of the LAb-CosmOrbitrap to decipher complex organic mixtures using single laser shot and a short transient are highlighted. In agreement with results provided by a commercial FTICR instrument in the laboratory, we demonstrate in this work the relevance of a space laser-CosmOrbitrap instrument for future planetary exploration.

© 2019 John Wiley & Sons, Ltd.

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