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Zonnevylle K, Schauwvlieghe PP, Van Calster J, et al. Co-occurrence of bilateral nodular anterior scleritis and large-vessel arteritis in a patient with TINU syndrome. GMS Ophthalmol Cases. 2019;9:Doc34doi: 10.3205/oc000123.
Zonnevylle, K., Schauwvlieghe, P. P., Van Calster, J., Lenaerts, J., & Peeters, D. (2019). Co-occurrence of bilateral nodular anterior scleritis and large-vessel arteritis in a patient with TINU syndrome. GMS ophthalmology cases, 9Doc34. https://doi.org/10.3205/oc000123
Zonnevylle, Kirsten, et al. "Co-occurrence of bilateral nodular anterior scleritis and large-vessel arteritis in a patient with TINU syndrome." GMS ophthalmology cases vol. 9 (2019): Doc34. doi: https://doi.org/10.3205/oc000123
Zonnevylle K, Schauwvlieghe PP, Van Calster J, Lenaerts J, Peeters D. Co-occurrence of bilateral nodular anterior scleritis and large-vessel arteritis in a patient with TINU syndrome. GMS Ophthalmol Cases. 2019 Oct 25;9:Doc34. doi: 10.3205/oc000123. eCollection 2019. PMID: 31728261; PMCID: PMC6839028.
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GMS Ophthalmol Cases. 2019 Oct 25;9:Doc34. doi: 10.3205/oc000123. eCollection 2019.

Co-occurrence of bilateral nodular anterior scleritis and large-vessel arteritis in a patient with TINU syndrome.

GMS ophthalmology cases

Kirsten Zonnevylle, Pieter-Paul Schauwvlieghe, Joachim Van Calster, Jan Lenaerts, Domien Peeters

Affiliations

  1. Ophthalmology, University Hospitals Leuven, Belgium.
  2. Department of Rheumatology, University Hospitals Leuven, KU Leuven, Belgium.
  3. Reuma-Instituut Hasselt, Belgium.
  4. Nephrology, Sint Trudo Hospital, Sint-Truiden, Belgium.

PMID: 31728261 PMCID: PMC6839028 DOI: 10.3205/oc000123

Abstract

We present a case of tubulointerstitial nephritis and uveitis (TINU) with nodular anterior scleritis and large-vessel arteritis. A 67-year-old patient was admitted to the hospital with high fever, thoracic pain, and weakness. Bilateral anterior uveitis was seen at that time. Laboratory examination showed acute renal failure. A renal biopsy was performed and showed pathognomonic signs of tubulointerstitial nephritis (TIN). Six months later, she developed ocular inflammation suggestive of nodular scleritis. One year after hospital admission, she presented with large-vessel arteritis. We describe a case of TINU with co-occurrence of scleritis and large-vessel arteritis.

Copyright © 2019 Zonnevylle et al.

Keywords: arteritis; interstitial nephritis; scleritis; tubulointerstitial nephritis and uveitis syndrome; uveitis

Conflict of interest statement

The authors declare that they have no competing interests.

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