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Sarveazad A, Agah S, Babahajian A, et al. Predictors of 5 year survival rate in hepatocellular carcinoma patients. J Res Med Sci. 2019;24:86doi: 10.4103/jrms.JRMS_1017_18.
Sarveazad, A., Agah, S., Babahajian, A., Amini, N., & Bahardoust, M. (2019). Predictors of 5 year survival rate in hepatocellular carcinoma patients. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2486. https://doi.org/10.4103/jrms.JRMS_1017_18
Sarveazad, Arash, et al. "Predictors of 5 year survival rate in hepatocellular carcinoma patients." Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences vol. 24 (2019): 86. doi: https://doi.org/10.4103/jrms.JRMS_1017_18
Sarveazad A, Agah S, Babahajian A, Amini N, Bahardoust M. Predictors of 5 year survival rate in hepatocellular carcinoma patients. J Res Med Sci. 2019 Oct 25;24:86. doi: 10.4103/jrms.JRMS_1017_18. eCollection 2019. PMID: 31741658; PMCID: PMC6856560.
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J Res Med Sci. 2019 Oct 25;24:86. doi: 10.4103/jrms.JRMS_1017_18. eCollection 2019.

Predictors of 5 year survival rate in hepatocellular carcinoma patients.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Arash Sarveazad, Shahram Agah, Asrin Babahajian, Naser Amini, Mansour Bahardoust

Affiliations

  1. Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
  2. Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
  3. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
  4. Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.

PMID: 31741658 PMCID: PMC6856560 DOI: 10.4103/jrms.JRMS_1017_18

Abstract

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common primary hepatic malignancies and growing challenges of global health. In this study, for the first time in Iran, we investigated the 5-year survival rate and prognostic factors in patients with HCC.

MATERIALS AND METHODS: In this historical cohort study, we examined the medical records of 227 HCC patients who were registered in the central tumor registry of our institution from September 2007 to September 2017. Demographic data, clinical parameters, received treatments, and survival curves from time of diagnosis were evaluated. Kaplan-Meier was used for univariate analysis, and multivariable analysis was performed by Cox regression.

RESULTS: A total of 208 (91.63%) patients were dead. The 5-year survival rate was estimated 19 (8.37%). The average follow-up in this study was 14.3 months. Overall median survival rate was 12.1 months. Univariate analysis showed that tumor size, metastasis, number of involved lymph node, hepatitis type, and treatment were significantly related to the survival rate, and Cox regression analysis revealed that the tumor size >3 cm (hazard ratio [HR] = 3.06, 95% confidence interval [CI] = 1.68-4.97;

CONCLUSION: Results of this study will help estimate survival rates for patients with HCC according to their clinical status.

Copyright: © 2019 Journal of Research in Medical Sciences.

Keywords: Five-year survival rate; hepatocellular carcinomas; prognostic factors

Conflict of interest statement

There are no conflicts of interest.

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