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Diagnostics (Basel). 2019 Nov 04;9(4). doi: 10.3390/diagnostics9040174.

Identification and Characterization of Nasal Polyposis and Mycoplasma Superinfection by Scanning Electron Microscopy and Nasal Cytology with Optical Microscopy: A Case Report.

Diagnostics (Basel, Switzerland)

Arturo Armone Caruso, Veronica Viola, Salvatore Del Prete, Sabato Leo, Daniela Marasco, Andrea Fulgione, Daniele Naviglio, Monica Gallo

Affiliations

  1. ENT Department, AIAS Structure of Afragola, Contrada Leutrec snc, 80021 Naples, Italy. [email protected].
  2. Department of Chemical Sciences, University of Naples Federico II, via Cintia, 21, 80126 Naples, Italy. [email protected].
  3. Service Biotech s.r.l., 80132 Napoli, Italy. [email protected].
  4. ENT Outpatient Clinic at Scafati Hospital ASL SA, 84018 Salerno, Italy. [email protected].
  5. Service Biotech s.r.l., 80132 Napoli, Italy. [email protected].
  6. Department of Agricultural Science, University of Naples Federico II, Via Università 100, 80045 Portici (NA), Italy. [email protected].
  7. Department of Chemical Sciences, University of Naples Federico II, via Cintia, 21, 80126 Naples, Italy. [email protected].
  8. Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, via Pansini, 5, 80131 Naples, Italy. [email protected].

PMID: 31689994 PMCID: PMC6963757 DOI: 10.3390/diagnostics9040174

Abstract

Nasal polyposis is characterized by benign, non-cancerous and painless growths originating in the tissue of the nasal cavities and paranasal sinuses. Polyps arise from chronic inflammation due to asthma, recurrent infections, allergies, drug sensitivity or immune disorders. They can obstruct the nasal cavities and thus cause respiratory problems, a reduction in the sense of smell and susceptibility to infections. Furthermore, nasal polyps can recur. Hence the importance of using valid diagnostic methods. In this work, the diagnostic investigation carried out by scanning electron microscopy (SEM) and nasal cytology led, for the first time, to the identification of a mycoplasma superinfection on nasal polyposis.

Keywords: mycoplasma; nasal cytology; nasal polyposis; optical microscopy; scanning electron microscopy

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