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Case Rep Crit Care. 2019 Oct 30;2019:9594289. doi: 10.1155/2019/9594289. eCollection 2019.

Pneumonia, an Unusual Initial Presentation of Neonatal Herpes Infection.

Case reports in critical care

Franck Kouadio, Gil Klinger

Affiliations

  1. Neonatal Intensive Care Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.
  2. Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israel.

PMID: 31781406 PMCID: PMC6875420 DOI: 10.1155/2019/9594289

Abstract

Neonatal herpes simplex virus (HSV) infection is a life-threatening infection with high morbidity and mortality rates. Neonatal herpes, most commonly due to HSV type 2, is a multi-system disease; however, initial pulmonary presentation is extremely unusual. We describe an infant presenting with progressive respiratory distress, which was the dominant clinical feature of HSV infection during the first days of life. Sepsis work-up and antibiotic treatment were immediately initiated; however, antiviral treatment was not given until the infant's death. HSV type 1 was isolated in nasopharyngeal and endotracheal aspirates. HSV pneumonia should be considered in a newborn with respiratory deterioration not compatible with common neonatal respiratory diseases.

Copyright © 2019 Franck Kouadio and Gil Klinger.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

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