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Clark A, Leddy R, Spruill L, et al. Pilomatrixoma, a Rare Mimicker of Male Breast Cancer. J Clin Imaging Sci. 2019;9:46doi: 10.25259/JCIS_64_2019.
Clark, A., Leddy, R., Spruill, L., & Cluver, A. (2019). Pilomatrixoma, a Rare Mimicker of Male Breast Cancer. Journal of clinical imaging science, 946. https://doi.org/10.25259/JCIS_64_2019
Clark, Aurela, et al. "Pilomatrixoma, a Rare Mimicker of Male Breast Cancer." Journal of clinical imaging science vol. 9 (2019): 46. doi: https://doi.org/10.25259/JCIS_64_2019
Clark A, Leddy R, Spruill L, Cluver A. Pilomatrixoma, a Rare Mimicker of Male Breast Cancer. J Clin Imaging Sci. 2019 Nov 06;9:46. doi: 10.25259/JCIS_64_2019. eCollection 2019. PMID: 31819823; PMCID: PMC6884983.
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J Clin Imaging Sci. 2019 Nov 06;9:46. doi: 10.25259/JCIS_64_2019. eCollection 2019.

Pilomatrixoma, a Rare Mimicker of Male Breast Cancer.

Journal of clinical imaging science

Aurela Clark, Rebecca Leddy, Laura Spruill, Abbie Cluver

Affiliations

  1. Departments of Radiology, Medical University of South Carolina, Charleston, South Carolina, USA.
  2. Departments of Pathology, Medical University of South Carolina, Charleston, South Carolina, USA.

PMID: 31819823 PMCID: PMC6884983 DOI: 10.25259/JCIS_64_2019

Abstract

Pilomatrixoma or calcifying epithelioma of Malherbe is a benign skin tumor arising from the hair follicle; breast occurrence is considered a rarity. Clinically presenting as a palpable abnormality and with both benign and malignant mammographic and sonographic features, it can be easily misdiagnosed as a breast neoplasm. We report a very rare case of pilomatrixoma of the male breast in a 36-year-old male presenting with a firm, superficial nodule in the upper outer quadrant. Though the sonographic trifecta of imaging features (shape- margins-orientation/oval, circumscribed mass, parallel to the skin) is consistent with a benign lesion, a histologic diagnosis was warranted based on its most suspicious feature of internal pleomorphic calcifications. Pathologic diagnosis revealed the uncommon benign entity of pilomatrixoma in the male breast. Our patient was recommended for surgical excision based on current literature recommendations for management in most reports of pilomatrixoma. One alternative recommendation presented in a single report of pilomatrixoma in the breast supported follow-up imaging based on benign imaging characteristics.

© 2019 Published by Scientific Scholar on behalf of Journal of Clinical Imaging Science.

Keywords: Benign; Cancer; Male breast; Pilomatrixoma; Surgical excision

Conflict of interest statement

There are no conflicts of interest.

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