Best Pract Res Clin Gastroenterol. 2019 Oct - Dec;42:101610. doi: 10.1016/j.bpg.2019.04.003. Epub 2019 Apr 17.
Best practice & research. Clinical gastroenterology
Kathryn Oakland
PMID: 31785737 DOI: 10.1016/j.bpg.2019.04.003
Upper gastrointestinal bleeding (UGIB) develops in the oesophagus, stomach or duodenum and has an incidence of 47/100,000. Lower GIB (LGIB) develops in the small bowel, colon or anorectum and has an incidence of 33/100,000. Where the incidence of UGIB has fallen, driven by helicobacter pylori eradication and the use of proton pump inhibitors, the incidence of LGIB may be increasing. Interventions such as early endoscopy, risk assessment and national guidelines have improved clinical outcomes but have had limited impact on the economic burden of GIB. Previously LGIB was thought to be less severe than UGIB, but contemporary data suggest that patients with LGIB tend to have a longer length of hospital stay and may be at higher risk of death or re-bleeding.
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