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Merikangas KR, Stevens D, Fenton B. Comorbidity of Alcoholism and Anxiety Disorders: The Role of Family Studies. Alcohol Health Res World. 1996;20(2):100-106
Merikangas, K. R., Stevens, D., & Fenton, B. (1996). Comorbidity of Alcoholism and Anxiety Disorders: The Role of Family Studies. Alcohol health and research world, 20(2), 100-106.
Merikangas, Kathleen R, et al. "Comorbidity of Alcoholism and Anxiety Disorders: The Role of Family Studies." Alcohol health and research world vol. 20,2 (1996): 100-106.
Merikangas KR, Stevens D, Fenton B. Comorbidity of Alcoholism and Anxiety Disorders: The Role of Family Studies. Alcohol Health Res World. 1996;20(2):100-106. PMID: 31798138; PMCID: PMC6876502.
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Alcohol Health Res World. 1996;20(2):100-106.

Comorbidity of Alcoholism and Anxiety Disorders: The Role of Family Studies.

Alcohol health and research world

Kathleen R Merikangas, Denise Stevens, Brenda Fenton

Affiliations

  1. Kathleen R. Merikangas, Ph.D., is the director of the Genetic Epidemiology Research Unit in the Departments of Epidemiology and Psychiatry at Yale University School of Medicine, New Haven, Connecticut. Denise Stevens, Ph.D., is an associate research scientist and Brenda Fenton, M.Sc., is a research associate in the Department of Epidemiology at Yale University School of Medicine, New Haven, Connecticut.

PMID: 31798138 PMCID: PMC6876502

Abstract

People with alcoholism frequently also suffer from an anxiety disorder. The mechanisms underlying this comorbidity remain unclear. Clinical findings indicate that anxiety disorders may lead to the development of alcoholism. Conversely, alcoholism may contribute to the development of anxiety symptoms. Family studies have reported elevated rates of anxiety disorders in the relatives of patients with alcoholism and vice versa, suggesting that both disorders may share some susceptibility factors. The Yale Family Study of the comorbidity of alcoholism and anxiety confirmed these observations. The study also found gender-specific differences in the risk for some comorbid anxiety disorders. Moreover, the relatives of people with alcohol dependence or anxiety were at increased risk for alcohol dependence but not alcohol abuse.

Keywords: AOD dependence; anxiety state; comorbidity; family study; gender differences; hereditary factors; prevalence; risk factors; treatment

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